Jonatan Tuncel
Overview
Explore the profile of Jonatan Tuncel including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
20
Citations
525
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Norin U, Rintisch C, Meng L, Forster F, Ekman D, Tuncel J, et al.
Nat Commun
. 2021 Jan;
12(1):610.
PMID: 33504785
The introduction of the CTLA-4 recombinant fusion protein has demonstrated therapeutic effects by selectively modulating T-cell activation in rheumatoid arthritis. Here we show, using a forward genetic approach, that a...
2.
Tuncel J, Holmberg J, Haag S, Hopkins M, Wester-Rosenlof L, Carlsen S, et al.
Arthritis Res Ther
. 2020 Apr;
22(1):95.
PMID: 32345366
Background: CD4 T cells play a central role during the early stages of rheumatoid arthritis (RA), but to which extent they are required for the perpetuation of the disease is...
3.
Tuncel J, Benoist C, Mathis D
J Exp Med
. 2019 Apr;
216(6):1328-1344.
PMID: 30988052
Perinatal T cells broadly access nonlymphoid tissues, where they are exposed to sessile tissue antigens. To probe the outcome of such encounters, we examined the defective elimination of self-reactive clones...
4.
Yau A, Tuncel J, Holmdahl R
Am J Pathol
. 2017 Mar;
187(5):987-998.
PMID: 28315676
Rheumatoid arthritis is a complex disease associated with >100 risk loci, with the strongest association from the major histocompatibility complex (MHC) region. Here, we analyzed a new genetic association in...
5.
Tuncel J, Haag S, Holmdahl R
Eur J Immunol
. 2016 Dec;
47(3):563-574.
PMID: 28012172
Polymorphisms in the MHC class II (MHCII) genes are strongly associated with rheumatoid arthritis, supporting the importance of autoreactive T helper (Th) cells for the development of this disease. Here,...
6.
Yau A, Tuncel J, Haag S, Norin U, Houtman M, Padyukov L, et al.
Proc Natl Acad Sci U S A
. 2016 Jun;
113(26):E3716-24.
PMID: 27303036
Genome-wide association studies have revealed many genetic loci associated with complex autoimmune diseases. In rheumatoid arthritis (RA), the MHC gene HLA-DRB1 is the strongest candidate predicting disease development. It has...
7.
Tuncel J, Haag S, Hoffmann M, Yau A, Hultqvist M, Olofsson P, et al.
PLoS One
. 2016 May;
11(5):e0155936.
PMID: 27227821
Background: To facilitate the development of therapies for rheumatoid arthritis (RA), the Innovative Medicines Initiative BTCure has combined the experience from several laboratories worldwide to establish a series of protocols...
8.
Haag S, Tuncel J, Thordardottir S, Mason D, Yau A, Dobritzsch D, et al.
J Immunol
. 2015 Feb;
194(6):2539-50.
PMID: 25672758
Rheumatoid arthritis (RA) is associated with amino acid variants in multiple MHC molecules. The association to MHC class II (MHC-II) has been studied in several animal models of RA. In...
9.
Natural polymorphisms in Tap2 influence negative selection and CD4∶CD8 lineage commitment in the rat
Tuncel J, Haag S, Yau A, Norin U, Baud A, Lonnblom E, et al.
PLoS Genet
. 2014 Mar;
10(2):e1004151.
PMID: 24586191
Genetic variation in the major histocompatibility complex (MHC) affects CD4∶CD8 lineage commitment and MHC expression. However, the contribution of specific genes in this gene-dense region has not yet been resolved....
10.
Haag S, Schneider N, Mason D, Tuncel J, Andersson I, Peters E, et al.
Arthritis Rheumatol
. 2014 Jan;
66(6):1440-9.
PMID: 24470447
Objective: To investigate type II collagen (CII) as a joint-specific target of the anti-citrullinated protein antibody (ACPA) response in rheumatoid arthritis (RA). Methods: Potential citrullinated neoepitopes were identified by high-resolution...