Peter M van Endert
Overview
Explore the profile of Peter M van Endert including associated specialties, affiliations and a list of published articles.
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Articles
17
Citations
753
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0
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Recent Articles
1.
Vear A, Chakraborty A, Fahimi F, Ferens D, Widdop R, Samuel C, et al.
Front Immunol
. 2024 Oct;
15:1466692.
PMID: 39430768
The enzyme, insulin regulated aminopeptidase (IRAP), is expressed in multiple immune cells such as macrophages, dendritic cells and T cells, where it plays a role in regulating the innate and...
2.
Montealegre S, van Endert P
Front Immunol
. 2019 Jan;
9:3098.
PMID: 30666258
Major histocompatibility complex class I (MHC I) molecules are glycoproteins that display peptide epitopes at the cell surface of nucleated cells for recognition by CD8 T cells. Like other cell...
3.
Ghez D, Lepelletier Y, Lambert S, Fourneau J, Blot V, Janvier S, et al.
J Virol
. 2006 Jul;
80(14):6844-54.
PMID: 16809290
Human T-cell lymphotropic virus type 1 (HTLV-1) is transmitted through a viral synapse and enters target cells via interaction with the glucose transporter GLUT1. Here, we show that Neuropilin-1 (NRP1),...
4.
Fruci D, Ferracuti S, Limongi M, Cunsolo V, Giorda E, Fraioli R, et al.
J Immunol
. 2006 Apr;
176(8):4869-79.
PMID: 16585582
Peptide trimming in the endoplasmic reticulum (ER), the final step required for the generation of most HLA class I-binding peptides, implicates the concerted action of two aminopeptidases, ERAP1 and ERAP2....
5.
Samino Y, Lopez D, Guil S, Saveanu L, van Endert P, Del Val M
J Biol Chem
. 2006 Jan;
281(10):6358-65.
PMID: 16407287
Viral antigens complexed with major histocompatibility complex (MHC) class I molecules are recognized by cytotoxic T lymphocytes on infected cells. Assays with synthetic peptides identify optimal MHC class I ligands...
6.
Hassainya Y, Garcia-Pons F, Kratzer R, Lindo V, Greer F, Lemonnier F, et al.
Diabetes
. 2005 Jun;
54(7):2053-9.
PMID: 15983206
Type 1 diabetes is thought to result from the destruction of beta-cells by autoantigen-specific T-cells. Observations in the NOD mouse model suggest that CD8+ cytotoxic T-cells play an essential role...
7.
Saveanu L, Carroll O, Lindo V, Del Val M, Lopez D, Lepelletier Y, et al.
Nat Immunol
. 2005 May;
6(7):689-97.
PMID: 15908954
The generation of many HLA class I peptides entails a final trimming step in the endoplasmic reticulum that, in humans, is accomplished by two 'candidate' aminopeptidases. We show here that...
8.
Mannering S, Morris J, Stone N, Jensen K, van Endert P, Harrison L
Ann N Y Acad Sci
. 2005 Feb;
1037:16-21.
PMID: 15699488
The ability to measure proliferation of autoantigen-specific T cells is critical for the evaluation of cellular immune function. Using a novel, sensitive, CFSE-based assay, we were able to directly quantitate...
9.
Culina S, Lauvau G, Gubler B, van Endert P
J Biol Chem
. 2004 Oct;
279(52):54210-5.
PMID: 15494401
The assembly of MHC class I molecules with beta(2)-microglobulin and peptides is assisted by the housekeeping chaperones calnexin, calreticulin, and Erp57 and the dedicated accessory protein, tapasin. Tapasin and calreticulin...
10.
Lemaitre F, Viguier M, Cho M, Fourneau J, Maillere B, Kourilsky P, et al.
Eur J Immunol
. 2004 Sep;
34(10):2941-9.
PMID: 15368300
MHC class II tetramers are attractive tools to study antigen-specific CD4(+) T cell responses in various clinical situations in humans. HLA-DRA1*0101/DRB1*0401 MHC class II heterodimers were produced as empty molecules...