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Peter M Carlton

Explore the profile of Peter M Carlton including associated specialties, affiliations and a list of published articles. Areas
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Articles 26
Citations 2037
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Recent Articles
1.
Rodriguez-Reza C, Sato-Carlton A, Carlton P
Curr Biol . 2024 Oct; 34(21):4998-5016.e6. PMID: 39395418
Sensing and control of size are critical for cellular function and survival. A striking example of size sensing occurs during meiosis in the nematode Caenorhabditis elegans. C. elegans chromosomes compare...
2.
Guo H, Stamper E, Sato-Carlton A, Shimazoe M, Li X, Zhang L, et al.
Elife . 2022 Jun; 11. PMID: 35758641
In the first meiotic cell division, proper segregation of chromosomes in most organisms depends on chiasmata, exchanges of continuity between homologous chromosomes that originate from the repair of programmed double-strand...
3.
Carlton P, Davis R, Ahmed S
Genetics . 2022 Mar; 221(1). PMID: 35323874
The nematode Caenorhabditis elegans has shed light on many aspects of eukaryotic biology, including genetics, development, cell biology, and genomics. A major factor in the success of C. elegans as...
4.
Kafer G, Tanaka Y, Rillo-Bohn R, Shimizu E, Hasegawa K, Carlton P
J Cell Sci . 2020 Nov; 133(24). PMID: 33199519
During the transition from pluripotency to a lineage-committed state, chromatin undergoes large-scale changes in structure, involving covalent modification of histone tails, use of histone variants and gene position changes with...
5.
Takemoto K, Imai Y, Saito K, Kawasaki T, Carlton P, Ishiguro K, et al.
PLoS Genet . 2020 Feb; 16(2):e1008640. PMID: 32092049
Meiotic recombination is essential for faithful segregation of homologous chromosomes during gametogenesis. The progression of recombination is associated with dynamic changes in meiotic chromatin structures. However, whether Sycp2, a key...
6.
Carlton P
Biophys Rev . 2017 May; 5(4):313-322. PMID: 28510112
Chromosomes undergoing meiosis are defined by a macromolecular protein assembly called the synaptonemal complex which holds homologs together and carries out important meiotic functions. By retaining the molecular specificity, multiplexing...
7.
Kafer G, Carlton P, Lehnert S
Placenta . 2015 Sep; 36(11):1325-8. PMID: 26363621
The histone variant H2A.Z is important in establishing new chromatin environments necessary for permitting changes in gene expression and thus differentiation in mouse embryonic stem (mES) cells. In this study...
8.
Schachtrup C, Ryu J, Mammadzada K, Khan A, Carlton P, Perez A, et al.
Nat Neurosci . 2015 Jun; 18(8):1077-80. PMID: 26120963
Astrocytes modulate neuronal activity and inhibit regeneration. We show that cleaved p75 neurotrophin receptor (p75(NTR)) is a component of the nuclear pore complex (NPC) required for glial scar formation and...
9.
Sato-Carlton A, Li X, Crawley O, Testori S, Martinez-Perez E, Sugimoto A, et al.
PLoS Genet . 2014 Oct; 10(10):e1004638. PMID: 25340746
Prior to the meiotic divisions, dynamic chromosome reorganizations including pairing, synapsis, and recombination of maternal and paternal chromosome pairs must occur in a highly regulated fashion during meiotic prophase. How...
10.
Zhang W, Miley N, Zastrow M, MacQueen A, Sato A, Nabeshima K, et al.
PLoS Genet . 2012 Aug; 8(8):e1002880. PMID: 22912597
During meiosis, chromosomes align with their homologous pairing partners and stabilize this alignment through assembly of the synaptonemal complex (SC). Since the SC assembles cooperatively yet is indifferent to homology,...