Peter J van den Elsen
Overview
Explore the profile of Peter J van den Elsen including associated specialties, affiliations and a list of published articles.
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71
Citations
2353
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Recent Articles
1.
Hos B, Tondini E, Camps M, Rademaker W, van den Bulk J, Ruano D, et al.
Cell Rep
. 2022 Nov;
41(8):111680.
PMID: 36417866
No abstract available.
2.
Hos B, Tondini E, Camps M, Rademaker W, van den Bulk J, Ruano D, et al.
Cell Rep
. 2022 Oct;
41(2):111485.
PMID: 36223747
We report an approach to identify tumor-specific CD4 T cell neo-epitopes of both mouse and human cancer cells by analysis of major histocompatibility complex (MHC) class II-eluted natural peptides. MHC...
3.
Ommering B, van den Elsen P, van der Zee J, Jost C, Dekker F
Med Sci Educ
. 2019 Apr;
28(2):451-455.
PMID: 31007968
Physician-scientists are urgently needed to make progress in the dynamic world of medical healthcare. Currently, there is a worldwide shortage in physicians pursuing a scientific career. Actively engaging students in...
4.
Vijayan S, Sidiq T, Yousuf S, van den Elsen P, Kobayashi K
Immunogenetics
. 2019 Feb;
71(3):273-282.
PMID: 30706093
Major histocompatibility complex (MHC) class I and class II molecules play critical roles in the activation of the adaptive immune system by presenting antigens to CD8+ and CD4+ T cells,...
5.
Wijdeven R, van Luijn M, Wierenga-Wolf A, Akkermans J, van den Elsen P, Hintzen R, et al.
EMBO Rep
. 2018 Jul;
19(9).
PMID: 30021835
The cytokine interferon-γ (IFNγ) can induce expression of MHC class II (MHCII) on many different cell types, leading to antigen presentation to CD4 T cells and immune activation. This has...
6.
Swets M, Wouters A, Krijgsman D, van Vlierberghe R, Boot A, van Eendenburg J, et al.
Clin Immunol
. 2018 Jul;
194:80-86.
PMID: 30006120
HLA-G protein expression could play a role in evasion of tumor immune surveillance. Accumulating evidence demonstrates that HLA-G is expressed in different types of malignancies, including colorectal cancer (CRC). The...
7.
Sestito C, Breve J, van Eggermond M, Killestein J, Teunissen C, van Rossum J, et al.
J Neuroinflammation
. 2017 Dec;
14(1):257.
PMID: 29268771
Background: Leukocyte infiltration into the central nervous system is an important feature of multiple sclerosis (MS) pathology. Among the infiltrating cells, monocytes comprise the largest population and are considered to...
8.
de Jong R, Ewing M, de Vries M, Karper J, Bastiaansen A, Peters H, et al.
PLoS One
. 2017 Oct;
12(10):e0185820.
PMID: 29016683
Objective: Genetic P300/CBP-associated factor (PCAF) variation affects restenosis-risk in patients. PCAF has lysine acetyltransferase activity and promotes nuclear factor kappa-beta (NFκB)-mediated inflammation, which drives post-interventional intimal hyperplasia development. We studied...
9.
van Essen T, van Pelt S, Bronkhorst I, Versluis M, Nemati F, Laurent C, et al.
PLoS One
. 2016 Oct;
11(10):e0164292.
PMID: 27764126
Introduction: Uveal melanoma (UM) with an inflammatory phenotype, characterized by infiltrating leukocytes and increased human leukocyte antigen (HLA) expression, carry an increased risk of death due to metastases. These tumors...
10.
Swets M, Seneby L, Boot A, van Wezel T, Gelderblom H, van de Velde C, et al.
Hum Immunol
. 2016 Jun;
77(9):764-72.
PMID: 27245757
Expression of human leukocyte antigen-G (HLA-G) is a suggested mechanism used by tumor cells to escape from host immune recognition and destruction. Advances in the field have made it evident...