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Peter J Hornsby

Explore the profile of Peter J Hornsby including associated specialties, affiliations and a list of published articles. Areas
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Articles 66
Citations 1193
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Recent Articles
11.
Qiu Z, Farnsworth S, Mishra A, Hornsby P
Stem Cells Cloning . 2014 Jan; 6:19-29. PMID: 24426786
The development of the technology for derivation of induced pluripotent stem (iPS) cells from human patients and animal models has opened up new pathways to the better understanding of many...
12.
Navara C, Hornecker J, Grow D, Chaudhari S, Hornsby P, Ichida J, et al.
Cell Reprogram . 2013 Nov; 15(6):495-502. PMID: 24182315
Development of effective pluripotent stem cell-based therapies will require safety and efficacy testing in a clinically relevant preclinical model such as nonhuman primates (NHPs). Baboons and macaques are equally similar...
13.
Werminghaus P, Haase M, Hornsby P, Schinner S, Schott M, Malendowicz L, et al.
J Steroid Biochem Mol Biol . 2013 Sep; 139:7-15. PMID: 24063979
Hedgehog (Hh)-signaling pathway is important in embryonic development. Activation of Hh-signaling is associated with tumorigenesis. Recent studies demonstrate that Hh-signaling is involved in the development of the adrenal gland in...
14.
Shi Q, Hornsby P, Meng Q, VandeBerg J, VandeBerg J
Am J Cardiovasc Dis . 2013 Aug; 3(3):107-19. PMID: 23991345
A high-fat diet is a major risk factor for atherosclerosis. We conducted a longitudinal investigation to determine whether vascular endothelial senescence is involved in the mechanism by which a high-fat...
15.
Farnsworth S, Qiu Z, Mishra A, Hornsby P
Exp Biol Med (Maywood) . 2013 Apr; 238(3):276-84. PMID: 23598973
Induced pluripotent stem cells (iPS cells) are important for the future development of regenerative medicine involving autologous cell therapy. Before autologous cell therapy can be applied to human patients, suitable...
16.
Li Q, Kannan A, Das A, DeMayo F, Hornsby P, Young S, et al.
Endocrinology . 2012 Nov; 154(1):446-57. PMID: 23142810
Differentiation of endometrial stromal cells into decidual cells is a prerequisite for successful embryo implantation. Our previous studies in the mouse have shown that bone morphogenetic protein 2 (BMP2), a...
17.
Wu Y, Mishra A, Qiu Z, Farnsworth S, Tardif S, Hornsby P
Stem Cells Int . 2012 May; 2012:767195. PMID: 22577396
Among the various species from which induced pluripotent stem cells have been derived, nonhuman primates (NHPs) have a unique role as preclinical models. Their relatedness to humans and similar physiology,...
18.
Hornsby P
J Endocrinol . 2012 May; 214(2):113-9. PMID: 22573830
Adrenarche is a cell biological and endocrinological puzzle. The differentiation of the zona reticularis in childhood in humans requires special techniques for study because it is confined to humans and...
19.
Lewis K, Mele J, Hornsby P, Buffenstein R
Gerontology . 2012 May; 58(5):453-62. PMID: 22572398
Background: Studies comparing similar-sized species with disparate longevity may elucidate novel mechanisms that abrogate aging and prolong good health. We focus on the longest living rodent, the naked mole-rat. This...
20.
He Y, Wu Y, Mishra A, Acha V, Andrews T, Hornsby P
Ageing Res Rev . 2011 Nov; 11(1):1-9. PMID: 22115588
Cell- and tissue-based biosensors comprise genetically engineered proteins that are incorporated into cells ex vivo or into cells of tissues in vivo. They enable the investigator to sense levels of...