Peter Hohenstein
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Explore the profile of Peter Hohenstein including associated specialties, affiliations and a list of published articles.
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60
Citations
2256
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Recent Articles
1.
Trink Y, Urbach A, Dekel B, Hohenstein P, Goldberger J, Kalisky T
Int J Mol Sci
. 2024 Apr;
25(8).
PMID: 38674106
The significant heterogeneity of Wilms' tumors between different patients is thought to arise from genetic and epigenetic distortions that occur during various stages of fetal kidney development in a way...
2.
Gregoire E, De Cian M, Migale R, Perea-Gomez A, Schaub S, Bellido-Carreras N, et al.
Science
. 2023 Nov;
382(6670):600-606.
PMID: 37917714
Sex determination in mammals depends on the differentiation of the supporting lineage of the gonads into Sertoli or pregranulosa cells that govern testis and ovary development, respectively. Although the Y-linked...
3.
Wu S, Lee H, Szep-Bakonyi R, Colozza G, Boese A, Gert K, et al.
Exp Mol Med
. 2023 Jun;
55(6):1278-1280.
PMID: 37340143
No abstract available.
4.
Trink Y, Urbach A, Dekel B, Hohenstein P, Goldberger J, Kalisky T
Int J Mol Sci
. 2023 Feb;
24(4).
PMID: 36834944
Wilms' tumors are pediatric malignancies that are thought to arise from faulty kidney development. They contain a wide range of poorly differentiated cell states resembling various distorted developmental stages of...
5.
van der Sluis T, Beyrend G, van der Gracht E, Abdelaal T, Jochems S, Belderbos R, et al.
Cell Rep Med
. 2023 Feb;
4(3):100939.
PMID: 36796366
Immune checkpoint therapy (ICT) has the power to eradicate cancer, but the mechanisms that determine effective therapy-induced immune responses are not fully understood. Here, using high-dimensional single-cell profiling, we interrogate...
6.
Wu S, Lee H, Szep-Bakonyi R, Colozza G, Boese A, Gert K, et al.
Exp Mol Med
. 2022 Dec;
54(12):2188-2199.
PMID: 36494589
The generation of conditional alleles using CRISPR technology is still challenging. Here, we introduce a Short Conditional intrON (SCON, 189 bp) that enables the rapid generation of conditional alleles via...
7.
Oosterveen T, Garcao P, Moles-Garcia E, Soleilhavoup C, Travaglio M, Sheraz S, et al.
Stem Cell Reports
. 2021 Oct;
16(11):2718-2735.
PMID: 34678205
In Parkinson's disease (PD), substantia nigra (SN) dopaminergic (DA) neurons degenerate, while related ventral tegmental area (VTA) DA neurons remain relatively unaffected. Here, we present a methodology that directs the...
8.
Li H, Hohenstein P, Kuure S
Genes (Basel)
. 2021 Mar;
12(2).
PMID: 33672414
The adult mammalian kidney is a poorly regenerating organ that lacks the stem cells that could replenish functional homeostasis similarly to, e.g., skin or the hematopoietic system. Unlike a mature...
9.
Grabert K, Sehgal A, Irvine K, Wollscheid-Lengeling E, Ozdemir D, Stables J, et al.
J Immunol
. 2020 Nov;
205(11):3154-3166.
PMID: 33139489
The proliferation, differentiation, and survival of cells of the mononuclear phagocyte system (MPS; progenitors, monocytes, macrophages, and classical dendritic cells) are controlled by signals from the M-CSF receptor (CSF1R). Cells...
10.
Wineberg Y, Bar-Lev T, Futorian A, Ben-Haim N, Armon L, Ickowicz D, et al.
J Am Soc Nephrol
. 2020 Jul;
31(10):2278-2291.
PMID: 32651222
Background: During mammalian kidney development, nephron progenitors undergo a mesenchymal-to-epithelial transition and eventually differentiate into the various tubular segments of the nephron. Recently, Drop-seq single-cell RNA sequencing technology for measuring...