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Peter Helmbold

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Citations 418
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Recent Articles
1.
Deutschmeyer V, Schlaudraff N, Walesch S, Moyer J, Sokol A, Graumann J, et al.
Int J Cancer . 2024 Sep; 156(2):353-367. PMID: 39344659
Of the seven in absentia homologue (SIAH) family, three members have been identified in the human genome. In contrast to the E3 ubiquitin ligase encoding SIAH1 and SIAH2, little is...
2.
Toberer F, Winkler J, Haenssle H, Heinzel-Gutenbrunner M, Enk A, Hartschuh W, et al.
Acta Dermatovenerol Croat . 2022 Sep; 30(1):25-31. PMID: 36153716
Metabolic reprogramming mediated by hypoxia-inducible factors play a crucial role in many human cancers. HIF-1α is activated under hypoxic conditions and is considered a key regulator of oxygen homoeostasis during...
3.
Toberer F, Winkler J, Haenssle H, Heinzel-Gutenbrunner M, Enk A, Hartschuh W, et al.
Hautarzt . 2022 Jan; 73(4):283-290. PMID: 34997269
Metabolic reprogramming mediated by hypoxia-inducible factors and its downstream targets plays a crucial role in many human malignancies. Excessive proliferation of tumor cells under hypoxic conditions leads to metabolic reprogramming...
4.
Toberer F, Haenssle H, Laimer M, Heinzel-Gutenbrunner M, Enk A, Hartschuh W, et al.
Acta Derm Venereol . 2020 Jul; 100(15):adv00235. PMID: 32618346
This study analysed the expression of vascular endothelial growth factor-A (VEGF), VEGFR-2, and VEGFR-3 in primary cutaneous melanomas with positive and negative sentinel node status (SLN) (a total of 58...
5.
Toberer F, Haenssle H, Rutten A, Kazakov D, Kastnerova L, Enk A, et al.
Acta Derm Venereol . 2019 Oct; 99(13):1270-1274. PMID: 31612234
To shed more light on the pathogenesis of sebaceous carcinoma, we analysed the expression of proteins related to angiogenesis in 18 ocular and 22 extraocular sebaceous carcinomas using a broad...
6.
Walesch S, Richter A, Helmbold P, Dammann R
Cancers (Basel) . 2015 Jul; 7(3):1233-43. PMID: 26198249
Epigenetic inactivation of tumor-related genes is an important characteristic in the pathology of human cancers, including melanomagenesis. We analyzed the epigenetic inactivation of Claudin 11 (CLDN11) in malignant melanoma (MM)...
7.
Richter A, Haag T, Walesch S, Herrmann-Trost P, Marsch W, Kutzner H, et al.
Cancers (Basel) . 2013 Nov; 5(4):1566-76. PMID: 24252868
Merkel cell carcinoma (MCC) is one of the most aggressive cancers of the skin. RASSFs are a family of tumor suppressors that are frequently inactivated by promoter hypermethylation in various...
8.
Ugurel S, Mentzel T, Utikal J, Helmbold P, Mohr P, Pfohler C, et al.
Clin Cancer Res . 2013 Nov; 20(2):499-510. PMID: 24173542
Purpose: Dermatofibrosarcoma protuberans (DFSP) is a rare cutaneous tumor. COL1A1-PDGFB gene fusion is frequent in DFSP, rendering tumor cell proliferation and survival dependent on PDGFRβ (platelet-derived growth factor receptor β)...
9.
Toberer F, Werchau S, Christia E, Enk A, Schirmacher P, Helmbold P
J Am Acad Dermatol . 2013 Oct; 69(5):827-828. PMID: 24124821
No abstract available.
10.
Gaiser M, Schakel K, Helmbold P
Int J Dermatol . 2013 Apr; 52(5):587-8. PMID: 23590374
No abstract available.