Peter H Larsen
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Explore the profile of Peter H Larsen including associated specialties, affiliations and a list of published articles.
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19
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726
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Recent Articles
1.
Steenberghen H, De Beuckeleer S, Hellings N, Somers V, Van Breedam E, Ponsaerts P, et al.
Cytometry A
. 2024 Nov;
105(12):870-882.
PMID: 39503054
The water channel aquaporin 4 (AQP4) contributes to water flow and waste removal across the blood-brain barrier and its levels, organization and localization are perturbed in various neurological diseases, including...
2.
Verstraelen P, Garcia-Diaz Barriga G, Verschuuren M, Asselbergh B, Nuydens R, Larsen P, et al.
iScience
. 2020 Oct;
23(9):101542.
PMID: 33083769
Most neurological disorders display impaired synaptic connectivity. Hence, modulation of synapse formation may have therapeutic relevance. However, the high density and small size of synapses complicate their quantification. To improve...
3.
Larsen P, Boehlert B, Eto J, Hamachi-LaCommare K, Martinich J, Rennels L
Energy (Oxf)
. 2019 Nov;
147:1256-1277.
PMID: 31728076
This analysis integrates regional models of power system reliability, output from atmosphere-ocean general circulation models, and results from the Interruption Cost Estimate (ICE) Calculator to project long-run costs to electric...
4.
Verschuuren M, Verstraelen P, Garcia-Diaz Barriga G, Cilissen I, Coninx E, Verslegers M, et al.
Acta Neuropathol Commun
. 2019 Jun;
7(1):93.
PMID: 31164177
Therapeutic developments for neurodegenerative disorders are redirecting their focus to the mechanisms that contribute to neuronal connectivity and the loss thereof. Using a high-throughput microscopy pipeline that integrates morphological and...
5.
Dale E, Grunnet M, Pehrson A, Frederiksen K, Larsen P, Nielsen J, et al.
Brain Res
. 2017 Dec;
1689:1-11.
PMID: 29274875
The multimodal antidepressant vortioxetine is thought to mediate its pharmacological effects via 5-HT receptor agonism, 5-HT receptor partial agonism, 5-HT, 5-HT, 5-HT receptor antagonism and 5-HT transporter inhibition. Here we...
6.
Nielsen J, Fejgin K, Sotty F, Nielsen V, Mork A, Christoffersen C, et al.
Transl Psychiatry
. 2017 Dec;
7(11):1261.
PMID: 29187755
1q21.1 hemizygous microdeletion is a copy number variant leading to eightfold increased risk of schizophrenia. In order to investigate biological alterations induced by this microdeletion, we generated a novel mouse...
7.
Bastrup J, Larsen P
J Neurosci Methods
. 2017 Mar;
283:23-32.
PMID: 28342832
Background: Novel tissue clearing technologies have, for the first time, made it possible to study intact tissue samples. This approach provides a tool for further clarifying findings from animal models...
8.
Didriksen M, Fejgin K, Nilsson S, Birknow M, Grayton H, Larsen P, et al.
J Psychiatry Neurosci
. 2016 Jul;
42(1):48-58.
PMID: 27391101
Background: The hemizygous 22q11.2 microdeletion is a common copy number variant in humans. The deletion confers high risk for neurodevelopmental disorders, including autism and schizophrenia. Up to 41% of deletion...
9.
Nilsson S, Celada P, Fejgin K, Thelin J, Nielsen J, Santana N, et al.
Psychopharmacology (Berl)
. 2016 Mar;
233(11):2151-2163.
PMID: 26983414
Rationale: A microdeletion at locus 15q13.3 is associated with high incidence rates of psychopathology, including schizophrenia. A mouse model of the 15q13.3 microdeletion syndrome has been generated (Df[h15q13]/+) with translational...
10.
Crestey F, Frederiksen K, Jensen H, Dekermendjian K, Larsen P, Bastlund J, et al.
ACS Chem Neurosci
. 2015 Jun;
6(8):1302-8.
PMID: 26114759
Voltage-gated sodium channels (Nav) are crucial to the initiation and propagation of action potentials (APs) in electrically excitable cells, and during the past decades they have received considerable attention due...