Peter De Wulf
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Explore the profile of Peter De Wulf including associated specialties, affiliations and a list of published articles.
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Articles
23
Citations
1184
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0
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Recent Articles
1.
Damizia M, Moretta G, De Wulf P
Cell Death Discov
. 2023 Nov;
9(1):410.
PMID: 37935656
By responding to a host of adverse conditions, ranging from DNA damage to viral infection, transcription factor p53 supports genomic stability, cellular health, and survival. Not surprisingly, tumours across the...
2.
Handle F, Puhr M, Gruber M, Andolfi C, Schafer G, Klocker H, et al.
Am J Pathol
. 2023 Jun;
193(9):1284-1297.
PMID: 37301535
The atypical protein kinase/ATPase RIO kinase (RIOK)-1 is involved in pre-40S ribosomal subunit production, cell-cycle progression, and protein arginine N-methyltransferase 5 methylosome substrate recruitment. RIOK1 overexpression is a characteristic of...
3.
Smurova K, Damizia M, Irene C, Stancari S, Berto G, Perticari G, et al.
Nat Commun
. 2023 Jun;
14(1):3172.
PMID: 37263996
Kinetochores assemble on centromeres via histone H3 variant CENP-A and low levels of centromere transcripts (cenRNAs). The latter are ensured by the downregulation of RNA polymerase II (RNAPII) activity, and...
4.
Jurikova K, De Wulf P, Cusanelli E
Trends Genet
. 2021 Mar;
37(7):608-611.
PMID: 33663806
Long noncoding (lnc)RNAs derived from telomeres, the ends of linear eukaryotic chromosomes, help to maintain telomere length and stability by multiple means, including regulation of telomerase activity and recombination-based telomere...
5.
Smurova K, De Wulf P
Front Genet
. 2019 Jan;
9:674.
PMID: 30627137
The chromosomal loci known as centromeres (CEN) mediate the equal distribution of the duplicated genome between both daughter cells. Specifically, centromeres recruit a protein complex named the kinetochore, that bi-orients...
6.
Berto G, Ferreira-Cerca S, De Wulf P
Curr Genet
. 2018 Dec;
65(2):457-466.
PMID: 30515528
The atypical Rio1 protein kinases/ATPases, which exist in most archaea and eukaryotes, have been studied intensely to understand how they promote small ribosomal subunit (SSU) maturation. However, mutant and knockdown...
7.
Iacovella M, Bremang M, Basha O, Giaco L, Carotenuto W, Golfieri C, et al.
Nucleic Acids Res
. 2018 Jul;
46(15):7586-7611.
PMID: 30011030
The Saccharomyces cerevisiae kinase/adenosine triphosphatase Rio1 regulates rDNA transcription and segregation, pre-rRNA processing and small ribosomal subunit maturation. Other roles are unknown. When overexpressed, human ortholog RIOK1 drives tumor growth...
8.
Iacovella M, Golfieri C, Massari L, Busnelli S, Pagliuca C, Dal Maschio M, et al.
Nat Commun
. 2015 Apr;
6:6643.
PMID: 25851096
The conserved protein kinase Rio1 localizes to the cytoplasm and nucleus of eukaryotic cells. While the roles of Rio1 in the cytoplasm are well characterized, its nuclear function remains unknown....
9.
Thapa K, Oldani A, Pagliuca C, De Wulf P, Hazbun T
Genetics
. 2015 Feb;
200(1):79-90.
PMID: 25716979
Kinetochores are conserved protein complexes that bind the replicated chromosomes to the mitotic spindle and then direct their segregation. To better comprehend Saccharomyces cerevisiae kinetochore function, we dissected the phospho-regulated...
10.
Bock L, Pagliuca C, Kobayashi N, Grove R, Oku Y, Shrestha K, et al.
Nat Cell Biol
. 2012 May;
14(6):614-24.
PMID: 22561345
Kinetochores attach the replicated chromosomes to the mitotic spindle and orchestrate their transmission to the daughter cells. Kinetochore-spindle binding and chromosome segregation are mediated by the multi-copy KNL1(Spc105), MIS12(Mtw1) and...