Peter Castric
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Explore the profile of Peter Castric including associated specialties, affiliations and a list of published articles.
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11
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287
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Recent Articles
1.
Allison T, Castric P
Pathog Dis
. 2015 Nov;
74(1):ftv102.
PMID: 26527621
Strains of Pseudomonas aeruginosa that produce type IVa pili categorized as group I have the potential to covalently attach an O-antigen repeating unit to the pilin C-terminal residue. PCR, employing...
2.
Allison T, Conrad S, Castric P
Microbiology (Reading)
. 2015 Aug;
161(9):1780-1789.
PMID: 26297472
The group I pilin category is the most common type of type IVa pilus produced by Pseudomonas aeruginosa. The lateral surfaces of these pili are characterized by the presence of...
3.
Qutyan M, Henkel M, Horzempa J, Quinn M, Castric P
J Bacteriol
. 2010 Sep;
192(22):5972-81.
PMID: 20833803
PilO is an oligosaccharyl transferase (OTase) that catalyzes the O-glycosylation of Pseudomonas aeruginosa 1244 pilin by adding a single O-antigen repeating unit to the β carbon of the C-terminal residue...
4.
Horzempa J, Held T, Cross A, Furst D, Qutyan M, Neely A, et al.
Clin Vaccine Immunol
. 2008 Feb;
15(4):590-7.
PMID: 18272666
The O antigen is both a major structural outer membrane component and the dominant epitope of most gram-negative bacteria. Pseudomonas aeruginosa 1244 produces a type IV pilus and covalently links...
5.
Qutyan M, Paliotti M, Castric P
Mol Microbiol
. 2007 Nov;
66(6):1444-58.
PMID: 18005110
PilO of Pseudomonas aeruginosa 1244 catalyses the attachment of an O-antigen repeating unit to the beta-carbon of the pilin C-terminal residue, a serine. The present study was conducted to locate...
6.
Horzempa J, Dean C, Goldberg J, Castric P
J Bacteriol
. 2006 Jun;
188(12):4244-52.
PMID: 16740931
The pilin of Pseudomonas aeruginosa 1244 is glycosylated with an oligosaccharide that is structurally identical to the O-antigen repeating unit of this organism. Concordantly, the metabolic source of the pilin...
7.
Smedley 3rd J, Jewell E, Roguskie J, Horzempa J, Syboldt A, Stolz D, et al.
Infect Immun
. 2005 Nov;
73(12):7922-31.
PMID: 16299283
The opportunistic pathogen Pseudomonas aeruginosa is a leading cause of nosocomial pneumonia. Among its virulence factors, the type IV pili of P. aeruginosa strain 1244 contain a covalently linked, three-sugar...
8.
Horzempa J, Comer J, Davis S, Castric P
J Biol Chem
. 2005 Nov;
281(2):1128-36.
PMID: 16286455
The beta-carbon of the Pseudomonas aeruginosa 1244 pilin C-terminal Ser is a site of glycosylation. The present study was conducted to determine the pilin structures necessary for glycosylation. It was...
9.
DiGiandomenico A, Matewish M, Bisaillon A, Stehle J, Lam J, Castric P
Mol Microbiol
. 2002 Oct;
46(2):519-30.
PMID: 12406226
The structural similarity between the pilin glycan and the O-antigen of Pseudomonas aeruginosa 1244 suggested that they have a common metabolic origin. Mutants of this organism lacking functional wbpM or...
10.
Comer J, Marshall M, Blanch V, Deal C, Castric P
Infect Immun
. 2002 May;
70(6):2837-45.
PMID: 12010970
Previous work (P. Castric, F. J. Cassels, and R. W. Carlson, J. Biol. Chem. 276:26479-26485, 2001) has shown the Pseudomonas aeruginosa 1244 pilin glycan to be covalently bound to a...