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Peter B Ernst

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Articles 68
Citations 2275
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Recent Articles
1.
Zhang Z, Tanaka I, Nakahashi-Ouchida R, Ernst P, Kiyono H, Kurashima Y
Semin Immunopathol . 2024 Apr; 45(4-6):549-550. PMID: 38647672
No abstract available.
2.
Zhang Z, Tanaka I, Nakahashi-Ouchida R, Ernst P, Kiyono H, Kurashima Y
Semin Immunopathol . 2024 Jan; 45(4-6):493-507. PMID: 38170255
Glycoprotein 2 (GP2) is a widely distributed protein in the digestive tract, contributing to mucosal barrier maintenance, immune homeostasis, and antigen-specific immune response, while also being linked to inflammatory bowel...
3.
Umemoto S, Nakahashi-Ouchida R, Yuki Y, Kurokawa S, Machita T, Uchida Y, et al.
NPJ Vaccines . 2023 Jul; 8(1):106. PMID: 37488116
Respiratory syncytial virus (RSV) is a leading cause of upper and lower respiratory tract infection, especially in children and the elderly. Various vaccines containing the major transmembrane surface proteins of...
4.
Zhang Z, Ernst P, Kiyono H, Kurashima Y
Front Immunol . 2022 Oct; 13:937120. PMID: 36189267
Mast cells (MCs) are immune cells widely distributed in the body, accompanied by diverse phenotypes and functions. Committed mast cell precursors (MCPs) leave the bone marrow and enter the blood...
5.
Rios-Covian D, Butcher L, Ablack A, Den Hartog G, Matsubara M, Ly H, et al.
Antioxid Redox Signal . 2022 Jun; 38(1-3):183-197. PMID: 35754343
Though best known for its role in oxidative DNA damage repair, apurinic/apyrimidinic endonuclease 1 (APE1) is a multifunctional protein that regulates multiple host responses during oxidative stress, including the reductive...
6.
Zhang Z, Tanaka I, Pan Z, Ernst P, Kiyono H, Kurashima Y
Eur J Immunol . 2022 Apr; 52(7):1035-1046. PMID: 35476255
The pancreas contains exocrine glands, which release enzymes (e.g., amylase, trypsin, and lipase) that are important for digestion and islets, which produce hormones. Digestive enzymes and hormones are secreted from...
7.
Kamioka M, Goto Y, Nakamura K, Yokoi Y, Sugimoto R, Ohira S, et al.
Proc Natl Acad Sci U S A . 2022 Jan; 119(3). PMID: 35027453
Paneth cells are intestinal epithelial cells that release antimicrobial peptides, such as α-defensin as part of host defense. Together with mesenchymal cells, Paneth cells provide niche factors for epithelial stem...
8.
Campillo-Gimenez L, Rios-Covian D, Rivera-Nieves J, Kiyono H, Chu H, Ernst P
Front Cell Infect Microbiol . 2021 Dec; 11:752304. PMID: 34869061
Over the last several years, many advances have been made in understanding the role of bacteria in the pathogenesis of gastrointestinal cancers. Beginning with being recognized as the first bacterial...
9.
Den Hartog G, Butcher L, Ablack A, Pace L, Ablack J, Xiong R, et al.
Front Immunol . 2021 Feb; 11:553994. PMID: 33603730
Pathogenic intestinal bacteria lead to significant disease in humans. Here we investigated the role of the multifunctional protein, Apurinic/apyrimidinic endonuclease 1 (APE1), in regulating the internalization of bacteria into the...
10.
Fujimoto K, Kimura Y, Allegretti J, Yamamoto M, Zhang Y, Katayama K, et al.
Gastroenterology . 2021 Feb; 160(6):2089-2102.e12. PMID: 33577875
Background & Aims: Fecal microbiota transplantation (FMT) is an effective therapy for recurrent Clostridioides difficile infection (rCDI). However, the overall mechanisms underlying FMT success await comprehensive elucidation, and the safety...