Peter A Nigrovic
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Explore the profile of Peter A Nigrovic including associated specialties, affiliations and a list of published articles.
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199
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Recent Articles
1.
Nigrovic P
Semin Arthritis Rheum
. 2025 Mar;
:152685.
PMID: 40023668
Most inflammatory arthritides are systemic diseases. In an individual patient, however, disease flares are more common in joints affected previously, a phenomenon termed joint-specific memory. A key driver of localized...
2.
Darbousset R, Senkpeil L, Kuehn J, Balu S, Miglani D, Dillon E, et al.
bioRxiv
. 2025 Feb;
PMID: 39896646
Systemic sclerosis (SSc) is characterized by progressive fibrosis of skin, lung, and other organs and retains among the highest rates of mortality among autoimmune diseases. We identified activation of circulating...
3.
Lee J, Yang L, Kotzin J, Ahimovic D, Bale M, Nigrovic P, et al.
J Exp Med
. 2025 Jan;
222(4).
PMID: 39873673
Inflammatory cytokines are fundamental mediators of the organismal response to injury, infection, or other harmful stimuli. To elucidate the early and mostly direct transcriptional signatures of inflammatory cytokines, we profiled...
4.
Jarrot P, Kim J, Chan W, Heger L, Schommer N, Cunin P, et al.
Front Immunol
. 2024 Dec;
15:1466234.
PMID: 39654901
Objectives: Diffuse alveolar hemorrhage (DAH) is a life-threatening complication of systemic lupus erythematosus and small vessel vasculitis. We previously showed that neutrophil extracellular traps (NETs) were associated with the pathogenesis...
5.
Schnell J, Briviesca R, Kim T, Charbonnier L, Henderson L, van Wijk F, et al.
Nat Rev Rheumatol
. 2024 Dec;
21(1):9-21.
PMID: 39653758
Classic regulatory T (T) cells expressing CD4 and the hallmark transcription factor FOXP3 are integral to the prevention of multi-system autoimmunity. However, immune-mediated arthritis is often associated with increased numbers...
6.
Liu M, Brodeur K, Bledsoe J, Harris C, Joerger J, Weng R, et al.
J Allergy Clin Immunol
. 2024 Dec;
PMID: 39622297
Background: Overt immune activation by viral infections can lead to cytokine storm syndromes, such as hemophagocytic lymphohistiocytosis (HLH) and macrophage activation syndrome (MAS). Objective: We aimed to compare the immune...
7.
Nigrovic P
Arthritis Rheumatol
. 2024 Nov;
PMID: 39491365
Macrophage activation syndrome (MAS) is a state of immune hyperactivation that can result in life-threatening multisystem end-organ dysfunction. Often termed a "cytokine storm," MAS occurs among the rheumatic diseases most...
8.
Chinas M, Fernandez-Salinas D, Aguiar V, Nieto-Caballero V, Lefton M, Nigrovic P, et al.
HGG Adv
. 2024 Oct;
6(1):100375.
PMID: 39468794
Multiple lines of evidence indicate that ankylosing spondylitis (AS) is a lymphocyte-driven disease. However, which lymphocyte populations are critical in AS pathogenesis is not known. In this study, we aimed...
9.
Hoytema van Konijnenburg D, Nigrovic P, Zanoni I
Trends Immunol
. 2024 Oct;
45(11):871-891.
PMID: 39438172
The respiratory tract is exposed to infection from inhaled pathogens, including viruses, bacteria, and fungi. So far, a comprehensive assessment that integrates common and distinct aspects of the immune response...
10.
Fautrel B, Mitrovic S, De Matteis A, Bindoli S, Anton J, Belot A, et al.
Ann Rheum Dis
. 2024 Sep;
83(12):1614-1627.
PMID: 39317417
Methods: In May 2022, EULAR and PReS endorsed a proposal for a joint task force (TF) to develop recommendations for the diagnosis and management of sJIA and AOSD. The TF...