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Peter A Lawrence

Explore the profile of Peter A Lawrence including associated specialties, affiliations and a list of published articles. Areas
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Articles 39
Citations 890
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Recent Articles
1.
Casal J, Storer F, Lawrence P
Open Biol . 2023 Jun; 13(6):230105. PMID: 37311537
Planar cell polarity (PCP), the coordinated orientation of structures such as cilia, mammalian hairs or insect bristles, depends on at least two molecular systems. We have argued that these two...
2.
Chorro A, Verma B, Homfeldt M, Ibanez B, Lawrence P, Casal J
Open Biol . 2022 Dec; 12(10):220195. PMID: 36476047
The slope of a supracellular molecular gradient has long been thought to orient and coordinate planar cell polarity (PCP). Here we demonstrate and measure that gradient. Dachsous (Ds) is a...
3.
Pietra S, Ng K, Lawrence P, Casal J
Open Biol . 2020 Dec; 10(12):200290. PMID: 33295841
We investigate planar cell polarity (PCP) in the larval epidermis. The intricate pattern of denticles depends on only one system of PCP, the Dachsous/Fat system. Dachsous molecules in one cell...
4.
Lawrence P
Development . 2019 May; 146(9). PMID: 31072843
No abstract available.
5.
Lawrence P, Casal J, de Celis J, Morata G
Sci Rep . 2019 May; 9(1):7049. PMID: 31065001
We respond to a recent report by Abbasi and Marcus who present two main findings: first they argue that there is an organiser and a compartment boundary within the posterior...
6.
Lawrence P, Casal J
Development . 2018 Dec; 145(23). PMID: 30530515
Our aim in this short Primer is to explain the principles of planar cell polarity (PCP) in animal development. The literature in this small field is complex and specialized, but...
7.
Casal J, Ibanez-Jimenez B, Lawrence P
Development . 2018 Aug; 145(18). PMID: 30154173
Epithelial cells are polarised within the plane of the epithelium, forming oriented structures that have a coordinated and consistent polarity (planar cell polarity, PCP). In , at least two separate...
8.
Lawrence P, Morata G
Wilehm Roux Arch Dev Biol . 2017 Mar; 187(4):375-379. PMID: 28305008
We estimate the number of blastoderm cells which generate the thoracic imaginal discs ofDrosophila. At hatching the wing disc is twice the size of the haltere disc, but the results...
9.
Lawrence P
Cell . 2016 Dec; 167(6):1436-1439. PMID: 27912050
Francis' office window (at the Salk) commanded a panorama of the Pacific. "This grand natural scene was a physical correlate of Francis's intellectual world: wide-ranging, brilliantly lit, a little overawing,...
10.
Lawrence P
Curr Top Dev Biol . 2016 Mar; 116:617-31. PMID: 26970645
In the last 50 years, there have been many changes to the substance, conduct, and style of research. Many of these changes have proved disastrous to the life of scientists...