Peter A Appleby
Overview
Explore the profile of Peter A Appleby including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
119
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Recent Articles
1.
Appleby P, Shabir S, Southgate J, Walker D
J R Soc Interface
. 2015 Feb;
12(105).
PMID: 25694543
Epithelial tissue structure is the emergent outcome of the interactions between large numbers of individual cells. Experimental cell biology offers an important tool to unravel these complex interactions, but current...
2.
Appleby P
J Comput Neurosci
. 2013 Aug;
36(3):339-54.
PMID: 23942985
Unlike simpler organisms, C. elegans possesses several distinct chemosensory pathways and chemotactic mechanisms. These mechanisms and pathways are individually capable of driving chemotaxis in a chemical concentration gradient. However, it...
3.
Appleby P, Shabir S, Southgate J, Walker D
J R Soc Interface
. 2013 Jul;
10(86):20130487.
PMID: 23864504
Calcium signalling plays a central role in regulating a wide variety of cell processes. A number of calcium signalling models exist in the literature that are capable of reproducing a...
4.
Shabir S, Cross W, Kirkwood L, Pearson J, Appleby P, Walker D, et al.
Am J Physiol Renal Physiol
. 2013 May;
305(3):F396-406.
PMID: 23720349
In addition to its role as a physical barrier, the urothelium is considered to play an active role in mechanosensation. A key mechanism is the release of transient mediators that...
5.
Waddington A, Appleby P, de Kamps M, Cohen N
Front Comput Neurosci
. 2012 Nov;
6:88.
PMID: 23162457
Synfire chains have long been proposed to generate precisely timed sequences of neural activity. Such activity has been linked to numerous neural functions including sensory encoding, cognitive and motor responses....
6.
Appleby P
Biol Cybern
. 2012 Jul;
106(6-7):373-87.
PMID: 22824944
The nematode C. elegans has attracted a great deal of interest from the neuroscience community due to the simplicity of its nervous system, which in the hermaphrodite is composed of...
7.
Appleby P, Kempermann G, Wiskott L
PLoS Comput Biol
. 2011 Feb;
7(1):e1001063.
PMID: 21298080
Recently, we presented a study of adult neurogenesis in a simplified hippocampal memory model. The network was required to encode and decode memory patterns despite changing input statistics. We showed...
8.
Appleby P, Wiskott L
Network
. 2009 Sep;
20(3):137-61.
PMID: 19731146
Recently we presented a model of additive neurogenesis in a linear, feedforward neural network that performed an encoding-decoding memory task in a changing input environment. Growing the neural network over...
9.
Appleby P, Elliott T
Neural Comput
. 2007 Mar;
19(5):1362-99.
PMID: 17381270
Recently we presented a stochastic, ensemble-based model of spike-timing-dependent plasticity. In this model, single synapses do not exhibit plasticity depending on the exact timing of pre- and postsynaptic spikes, but...
10.
Appleby P, Elliott T
Neural Comput
. 2006 Aug;
18(10):2414-64.
PMID: 16907632
In earlier work we presented a stochastic model of spike-timing-dependent plasticity (STDP) in which STDP emerges only at the level of temporal or spatial synaptic ensembles. We derived the two-spike...