Pertti Lehikoinen
Overview
Explore the profile of Pertti Lehikoinen including associated specialties, affiliations and a list of published articles.
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12
Citations
279
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Recent Articles
1.
Tolvanen T, Yli-Kerttula T, Ujula T, Autio A, Lehikoinen P, Minn H, et al.
Eur J Nucl Med Mol Imaging
. 2010 Jan;
37(5):874-83.
PMID: 20069295
Purpose: Methyl-(11)C-choline ([(11)C]choline) is a radiopharmaceutical used for oncological PET studies. We investigated the biodistribution and biokinetics of [(11)C]choline and provide estimates of radiation doses in humans. Methods: The distribution...
2.
Ujula T, Salomaki S, Autio A, Luoto P, Tolvanen T, Lehikoinen P, et al.
Mol Imaging Biol
. 2009 Oct;
12(3):259-68.
PMID: 19798536
Purpose: The aim of the study was to compare (68)Ga-chloride with 2-[(18)F]fluoro-2-deoxy-D: -glucose (FDG) for the imaging of pancreatic xenografts. Procedures: Rats with subcutaneous human pancreatic adenocarcinoma xenografts were evaluated...
3.
Lindholm P, Lapela M, Nagren K, Lehikoinen P, Minn H, Jyrkkio S
Nucl Med Commun
. 2009 Mar;
30(1):30-6.
PMID: 19306512
Objective: Breast cancer is one of the principal oncological challenges in the Western world. Currently, there are only a few reliable predictive methods for monitoring treatment. We investigated the ability...
4.
Hietala J, Nyman M, Eskola O, Laakso A, Gronroos T, Oikonen V, et al.
Mol Imaging Biol
. 2005 Sep;
7(4):262-72.
PMID: 16155744
Purpose: This study was conducted to develop a new positron emission tomography (PET) method to visualize neurokinin-1 (NK(1)) receptor systems in the human brain in vivo in order to examine...
5.
Solin O, Eskola O, Hamill T, Bergman J, Lehikoinen P, Gronroos T, et al.
Mol Imaging Biol
. 2004 Nov;
6(6):373-84.
PMID: 15564148
Purpose: To develop and characterize a radiolabelled Substance-P antagonist useful for quantitation of neurokinin-1 receptors in the brain via PET imaging. Procedure: [18F]SPA-RQ (Substance-P antagonist - receptor quantifier) was synthesized...
6.
Stolen K, Kemppainen J, Kalliokoski K, Hallsten K, Luotolahti M, Karanko H, et al.
J Card Fail
. 2004 Apr;
10(2):132-40.
PMID: 15101025
Background: Exercise intolerance is a hallmark symptom in patients with heart failure; however, myocardial factors contributing to the limited exercise capacity are not fully characterized. Methods: Twenty patients with stable...
7.
Eskola O, Gronroos T, Bergman J, Haaparanta M, Marjamaki P, Lehikoinen P, et al.
Nucl Med Biol
. 2004 Jan;
31(1):103-10.
PMID: 14741575
(1R,2S)-4-[18F]fluorometaraminol (4-[18F]FMR), a tracer for cardiac sympathetic innervation, was synthesized by electrophilic aromatic substitution. A trimethylstannyl precursor, protected with tert-butoxycarbonyl protecting groups, was radiofluorinated with high specific radioactivity [18F]F2. Specific...
8.
Sutinen E, Nurmi M, Roivainen A, Varpula M, Tolvanen T, Lehikoinen P, et al.
Eur J Nucl Med Mol Imaging
. 2003 Nov;
31(3):317-24.
PMID: 14628097
Carbon-11 choline has recently been introduced as a potential tracer for tumour imaging with positron emission tomography (PET). We evaluated the kinetics of the uptake of [(11)C]choline in prostate cancer...
9.
Roivainen A, Parkkola R, Yli-Kerttula T, Lehikoinen P, Viljanen T, Mottonen T, et al.
Arthritis Rheum
. 2003 Nov;
48(11):3077-84.
PMID: 14613269
Objective: To compare positron emission tomography (PET) and magnetic resonance imaging (MRI) in the evaluation of inflammatory proliferation of synovium. Methods: Ten patients (mean +/- SD age 36 +/- 13...
10.
Stolen K, Kemppainen J, Ukkonen H, Kalliokoski K, Luotolahti M, Lehikoinen P, et al.
J Am Coll Cardiol
. 2003 Feb;
41(3):460-7.
PMID: 12575976
Objectives: The aim of this study was to determine the effect of exercise training on myocardial oxidative metabolism and efficiency in patients with idiopathic dilated cardiomyopathy (DCM) and mild heart...