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Per Brandtzaeg

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Zhang R, Alam S, Yu J, Scearce R, Lockwood B, Hwang K, et al.
Monoclon Antib Immunodiagn Immunother . 2016 Jul; 35(4):217-26. PMID: 27386924
Immunoglobulin A (IgA) antibodies exist in monomeric, dimeric, and secretory forms. Dimerization of IgA depends on a 15-kD polypeptide termed "joining (J) chain," which is also part of the binding...
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Skrede S, Steinsland H, Sommerfelt H, Aase A, Brandtzaeg P, Langeland N, et al.
BMC Infect Dis . 2014 Sep; 14:482. PMID: 25190096
Background: Enterotoxigenic Escherichia coli (ETEC) is an important cause of childhood diarrhea in resource-limited regions. It is also an important cause of diarrhea in travellers to these areas.To evaluate the...
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Brandtzaeg P
Front Immunol . 2013 Aug; 4:222. PMID: 23964273
Prevention of infections by vaccination remains a compelling goal to improve public health. Mucosal vaccines would make immunization procedures easier, be better suited for mass administration, and most efficiently induce...
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Brandtzaeg P
J Oral Microbiol . 2013 Mar; 5. PMID: 23487566
The two principal antibody classes present in saliva are secretory IgA (SIgA) and IgG; the former is produced as dimeric IgA by local plasma cells (PCs) in the stroma of...
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Nilssen D, Brandtzaeg P
PLoS One . 2012 Jan; 7(1):e29066. PMID: 22238587
Intraepithelial lymphocytes (IELs) bearing the γδ T-cell receptor are a unique intestinal subset whose function remains elusive. Here, we examine how they behave in AIDS and during various regimens of...
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Renz H, Brandtzaeg P, Hornef M
Nat Rev Immunol . 2011 Dec; 12(1):9-23. PMID: 22158411
The mucosal surfaces of the gut and airways have important barrier functions and regulate the induction of immunological tolerance. The rapidly increasing incidence of chronic inflammatory disorders of these surfaces,...
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Renz H, Autenrieth I, Brandtzaeg P, Cookson W, Holgate S, von Mutius E, et al.
J Allergy Clin Immunol . 2011 Nov; 128(6 Suppl):S27-49. PMID: 22118218
Over the last half century, a dramatic increase in the incidence of chronic inflammatory diseases, such as asthma, allergy, and irritable bowel syndrome, has rightfully led to concern about how...
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Brandtzaeg P
Adv Otorhinolaryngol . 2011 Aug; 72:20-4. PMID: 21865681
This brief review will focus on nasopharynx-associated lymphoid tissue as a unique inductive immune site for B cell responses and plasma cell generation. The anatomical and immunological characteristics of Waldeyer's...
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Brandtzaeg P
Eur J Pharmacol . 2011 Aug; 668 Suppl 1:S16-32. PMID: 21816150
During human evolution, the mucosal immune system developed two anti-inflammatory mechanisms: immune exclusion by secretory antibodies (SIgA and SIgM) to control epithelial colonization of microorganisms and inhibit penetration of harmful...