Penny Gordon-Larsen
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Explore the profile of Penny Gordon-Larsen including associated specialties, affiliations and a list of published articles.
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241
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10697
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Recent Articles
1.
Chen H, Highland H, Frankel E, Scartozzi A, Zhang X, Roshani R, et al.
Cell Genom
. 2025 Mar;
5(3):100784.
PMID: 40043711
Polygenic severe obesity (body mass index [BMI] ≥40 kg/m) has increased, especially in Hispanic/Latino populations, yet we know little about the underlying mechanistic pathways. We analyzed whole-blood multiomics data to...
2.
Guo B, Cai Y, Kim D, Smit R, Wang Z, Iyer K, et al.
medRxiv
. 2025 Mar;
PMID: 40034751
Polygenic risk scores (PRS) hold prognostic value for identifying individuals at higher risk of type 2 diabetes (T2D). However, further characterization is needed to understand the generalizability of T2D PRS...
3.
Park S, Wong M, Kiefe C, Gordon-Larsen P, Kershaw K
J Am Heart Assoc
. 2024 Nov;
13(22):e036035.
PMID: 39547998
Background: Adults who maintain ideal cardiovascular health (CVH) profiles up to midlife have lower risk of several chronic diseases and better quality of life. Some evidence suggests that individual-level exposures...
4.
Qi B, Cooper G, Thornton L, Zhang R, Yao S, Howard A, et al.
Br J Nutr
. 2024 Sep;
132(5):631-639.
PMID: 39308203
Disordered eating (DE) is associated with elevated cardiometabolic risk (CMR) factors, yet little is known about this association in non-Western countries. We examined the association between DE characteristics and CMR...
5.
Sprinkles J, Lulla A, Hullings A, Trujillo-Gonzalez I, Klatt K, Jacobs Jr D, et al.
Diabetes Care
. 2024 Sep;
47(11):1985-1994.
PMID: 39259767
Objective: The potential for choline metabolism to influence the development of diabetes has received increased attention. Previous studies on circulating choline metabolites and incident diabetes have been conducted in samples...
6.
Li C, Bishop T, Imamura F, Sharp S, Pearce M, Brage S, et al.
Lancet Diabetes Endocrinol
. 2024 Aug;
12(9):619-630.
PMID: 39174161
Background: Meat consumption could increase the risk of type 2 diabetes. However, evidence is largely based on studies of European and North American populations, with heterogeneous analysis strategies and a...
7.
Li Y, Wong K, Howard A, Gordon-Larsen P, Highland H, Graff M, et al.
HGG Adv
. 2024 Aug;
5(4):100338.
PMID: 39095990
Multivariable Mendelian randomization allows simultaneous estimation of direct causal effects of multiple exposure variables on an outcome. When the exposure variables of interest are quantitative omic features, obtaining complete data...
8.
Kim K, Joyce B, Zheng Y, Nannini D, Wang J, Gordon-Larsen P, et al.
Circulation
. 2024 Jun;
150(3):203-214.
PMID: 38934130
Background: Proximity to urban blue and green spaces has been associated with improved cardiovascular health; however, few studies have examined the role of race and socioeconomic status in these associations....
9.
Richardson A, Dubowitz T, Beyer K, Zhou Y, Kershaw K, Duck W, et al.
AJPM Focus
. 2024 Apr;
3(3):100209.
PMID: 38590394
Introduction: Historical maps of racialized evaluation of mortgage lending risk (i.e., redlined neighborhoods) have been linked to adverse health outcomes. Little research has examined whether living in historically redlined neighborhoods...
10.
Suzuki K, Hatzikotoulas K, Southam L, Taylor H, Yin X, Lorenz K, et al.
Nature
. 2024 Feb;
627(8003):347-357.
PMID: 38374256
Type 2 diabetes (T2D) is a heterogeneous disease that develops through diverse pathophysiological processes and molecular mechanisms that are often specific to cell type. Here, to characterize the genetic contribution...