Pengcui Li
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Explore the profile of Pengcui Li including associated specialties, affiliations and a list of published articles.
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76
Citations
457
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Recent Articles
1.
Liu C, Zhao L, Dong H, Hua Z, Wang Y, Wang Y, et al.
Front Bioeng Biotechnol
. 2025 Feb;
13:1485593.
PMID: 39963171
Introduction: The electric signals within the cartilage tissue are essential to biological systems and play a significant role in cartilage regeneration. Therefore, this study analyzed and investigated the reverse mechano-electrical...
2.
Lu C, Xu Y, Chen S, Guo L, Li P, Wei X, et al.
PLoS One
. 2025 Feb;
20(2):e0316824.
PMID: 39932908
Background: Osteoarthritis (OA) is a prevalent chronic joint disease for which there is a lack of effective treatments. In this study, we used Mendelian randomization analysis to identify circulating proteins...
3.
Huang J, Xu Y, Li Y, Pang Y, Ding X, Zhou R, et al.
FEBS Open Bio
. 2025 Feb;
PMID: 39895575
Several studies have previously shown that histone deacetylase 4 (HDAC4) can regulate endoplasmic reticulum stress-induced apoptosis through the activating transcription factor 4 (ATF4)/CAAT/enhancer binding protein homologous (CHOP) signaling pathway, thereby...
4.
Zhang C, Zhao R, Dong Z, Liu Y, Liu M, Li H, et al.
J Orthop Translat
. 2024 Nov;
49:207-217.
PMID: 39498143
Background: Chondrocyte hypertrophy is a potential target for osteoarthritis (OA) treatment, with Indian hedgehog (IHH), glioma-associated oncogene homolog (GLI), and hypoxia-inducible factor-2α (HIF-2α) being closely associated with chondrocyte hypertrophy during...
5.
Wang Y, Zhou R, Dong Z, Wang W, Guo L, Sun J, et al.
J Biol Chem
. 2024 Oct;
300(12):107941.
PMID: 39481602
HDAC4 is a class II histone deacetylation protein with a well-characterized role in chondrocyte differentiation and skeletal development, and dysregulated expression or haploinsufficiency of Hdac4 leads to skeletal formation and...
6.
Guo L, Li P, Rong X, Wei X
Chin Med J (Engl)
. 2024 Oct;
PMID: 39439390
The superficial zone (SFZ) of articular cartilage is an important interface that isolates deeper zones from the microenvironment of the articular cavity and is directly exposed to various biological and...
7.
Guo L, Zhuo X, Lu C, Guo H, Chen Z, Wu G, et al.
J Cell Mol Med
. 2024 Oct;
28(20):e70135.
PMID: 39428562
Exogenous administration of the histone deacetylation 4 (HDAC4) protein can effectively delay osteoarthritis (OA) progression. However, HDAC4 is unstable and easily degrades into N-terminal (HDAC4-NT) and C-terminal fragments, and the...
8.
Wang F, Yuan P, Gong Y, Zhang G, Li P, Jiao Q
Orthop Surg
. 2024 Aug;
16(10):2517-2525.
PMID: 39168855
Objective: Due to low prevalence and few studies, the morphologic risk factors for hip osteoarthritis (HOA) in Chinese population remain unknown. The purpose of this study was to investigate the...
9.
Li Y, Qiao X, Feng Y, Zhou R, Zhang K, Pan Y, et al.
Aging (Albany NY)
. 2024 Jul;
16(13):10841-10859.
PMID: 38967635
Previous studies have reported the correlation between gut microbiota (GM), GM-derived metabolites, and various intestinal and extra-intestinal cancers. However, limited studies have investigated the correlation between GM, GM-derived metabolites, and...
10.
Gu X, Li F, Che X, Wei X, Li P
BMC Musculoskelet Disord
. 2024 Jun;
25(1):467.
PMID: 38879481
Background: The present study evaluated whether the lack of histone deacetylase 4 (HDAC4) increases endoplasmic reticulum stress-induced chondrocyte apoptosis by releasing activating transcription factor 4 (ATF4) in human osteoarthritis (OA)...