Peng R Chen
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Explore the profile of Peng R Chen including associated specialties, affiliations and a list of published articles.
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146
Citations
4080
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Recent Articles
1.
Lou Z, Zhang Y, Liang X, Cao M, Ma Y, Chen P, et al.
J Am Chem Soc
. 2025 Mar;
PMID: 40036744
Immunotherapy efficacy in solid tumors varies greatly, influenced by the tumor microenvironment (TME) and the dynamic tumor-immune interactions within it. Decoding these interactions with minimal interference with native tissue architecture...
2.
Tos S, Osama M, Mantziaris G, Hajikarimloo B, Adeeb N, Kandregula S, et al.
Neurosurg Rev
. 2025 Feb;
48(1):276.
PMID: 40016553
Cerebral arteriovenous malformations (AVMs) are congenital vascular anomalies that can lead to severe complications, including hemorrhage and neurological deficits. This study compares the outcomes of microsurgical resection and stereotactic radiosurgery...
3.
Sconzo D, Ramirez-Velandia F, Muram S, Enriquez-Marulanda A, Adeeb N, Kandregula S, et al.
Neurosurg Rev
. 2025 Feb;
48(1):263.
PMID: 39985590
Seizures occur in 20-45% of patients with cerebral arteriovenous malformations (AVMs) and can potentially influence their quality of life. Some studies have suggested risk factors influencing their development, but the...
4.
Musmar B, Adeeb N, Abdalrazeq H, Roy J, Tjoumakaris S, Salim H, et al.
Eur Stroke J
. 2025 Feb;
:23969873251319924.
PMID: 39953956
Introduction: The impact of multiple feeding arteries on clinical outcomes of cerebral arteriovenous malformations (AVMs) is not well understood. This study aims to compare outcomes between AVMs with multiple versus...
5.
Musmar B, Adeeb N, Abdalrazeq H, Salim H, Salim H, Roy J, et al.
Int J Stroke
. 2025 Feb;
:17474930251323503.
PMID: 39948730
Background: Arteriovenous malformations (AVMs) are complex vascular anomalies with a high risk of hemorrhage and neurological deficits, especially when located in eloquent brain regions. The eloquence of an AVM location...
6.
Yu J, Liu H, Gao R, Wang T, Li C, Liu Y, et al.
Cell Chem Biol
. 2024 Dec;
32(1):157-173.e7.
PMID: 39740665
Research into mechanisms underlying sleep traditionally relies on electrophysiology and genetics. Because sleep can only be measured on whole animals by behavioral observations and physical means, no sleep research was...
7.
Tos S, Hajikarimloo B, Osama M, Mantziaris G, Adeeb N, Kandregula S, et al.
Clin Neurol Neurosurg
. 2024 Dec;
249:108669.
PMID: 39642799
Background: Spetzler-Martin (SM) Grade III brain arteriovenous malformations (BAVMs) represent a transitional risk zone between low- and high-grade BAVMs, characterized by diverse angioarchitecture. The primary treatment options are endovascular embolization,...
8.
Liu H, Fu Z, Han Y, Fang Y, Shen W, Chen Z, et al.
J Am Chem Soc
. 2024 Nov;
146(48):32933-32941.
PMID: 39561381
The recent advancements on membrane protein degraders (MPDs) have broadened the applicability of proteolysis-targeting chimeras (PROTACs) beyond intracellular proteins to include the previously "undruggable" cell-surface targets. However, the potential toxicity...
9.
Lin F, Yin S, Zhang Z, Yu Y, Fang H, Liang Z, et al.
Cell
. 2024 Nov;
187(26):7470-7491.e32.
PMID: 39504957
Although immunotherapy has revolutionized cancer treatment, its efficacy is affected by multiple factors, particularly those derived from the complexity and heterogeneity of the tumor-immune microenvironment (TIME). Strategies that simultaneously and...
10.
Li K, Xie X, Gao R, Chen Z, Yang M, Wen Z, et al.
Nat Chem
. 2024 Nov;
17(1):111-123.
PMID: 39501047
Resolving protein-protein interactions (PPIs) inside biomolecular condensates is crucial for elucidating their functions and regulation mechanisms. The transient nature of condensates and the multiple localizations of clients, however, have rendered...