Peng R Chen
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Explore the profile of Peng R Chen including associated specialties, affiliations and a list of published articles.
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146
Citations
4080
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Recent Articles
11.
Musmar B, Adeeb N, Roy J, Abdalrazeq H, Tjoumakaris S, Atallah E, et al.
J Neurointerv Surg
. 2024 Oct;
PMID: 39366733
Background: Arteriovenous malformations (AVMs) are uncommon cerebral lesions that can cause significant neurological complications. Surgical resection is the gold standard for treatment, but endovascular embolization and stereotactic radiosurgery (SRS) are...
12.
Jeong J, Bafor A, Freeman B, Chen P, Park E, Kim E
Biomedicines
. 2024 Aug;
12(8).
PMID: 39200259
Brain arteriovenous malformations (bAVMs) substantially increase the risk for intracerebral hemorrhage (ICH), which is associated with significant morbidity and mortality. However, the treatment options for bAVMs are severely limited, primarily...
13.
Guo W, Liu Y, Han Y, Tang H, Fan X, Wang C, et al.
Natl Sci Rev
. 2024 Jul;
11(7):nwae183.
PMID: 39055168
Ultrasensitive protein identification is of paramount importance in basic research and clinical diagnostics but remains extremely challenging. A key bottleneck in preventing single-molecule protein sequencing is that, unlike the revolutionary...
14.
Zhang Y, Liu S, Guo F, Qin S, Zhou N, Liu Z, et al.
J Am Chem Soc
. 2024 May;
146(22):15186-15197.
PMID: 38789930
Effective antitumor immunity hinges on the specific engagement between tumor and cytotoxic immune cells, especially cytotoxic T cells. Although investigating these intercellular interactions is crucial for characterizing immune responses and...
15.
Liu Z, Guo F, Zhu Y, Qin S, Hou Y, Guo H, et al.
Nat Commun
. 2024 Mar;
15(1):2712.
PMID: 38548729
In situ profiling of subcellular proteomics in primary living systems, such as native tissues or clinic samples, is crucial for understanding life processes and diseases, yet challenging due to methodological...
16.
Kolls B, Muir K, Savitz S, Wechsler L, Pilitsis J, Rahimi S, et al.
Trials
. 2024 Feb;
25(1):150.
PMID: 38419030
Background: Recruitment of participants is the greatest risk to completion of most clinical trials, with 20-40% of trials failing to reach the targeted enrollment. This is particularly true of trials...
17.
Zhu Y, Ding W, Chen Y, Shan Y, Liu C, Fan X, et al.
Nat Chem
. 2024 Feb;
16(4):533-542.
PMID: 38418535
Tryptophan (Trp) plays a critical role in the regulation of protein structure, interactions and functions through its π system and indole N-H group. A generalizable method for blocking and rescuing...
18.
Guo F, Qin S, Liu Z, Chen P, Fan X
Bioorg Chem
. 2024 Jan;
143:107088.
PMID: 38194902
Biomolecule labeling in living systems is crucial for understanding biological processes and discovering therapeutic targets. A variety of labeling warheads have been developed for multiple biological applications, including proteomics, bioimaging,...
19.
Weng Y, Chen W, Kong Q, Wang R, Zeng R, He A, et al.
Nat Chem Biol
. 2024 Jan;
20(5):615-623.
PMID: 38167916
Cellular context is crucial for understanding the complex and dynamic kinase functions in health and disease. Systematic dissection of kinase-mediated cellular processes requires rapid and precise stimulation ('pulse') of a...
20.
Becerril-Gaitan A, Bindal S, Parker S, Mullarkey M, Zeineddine H, Chen J, et al.
Stroke
. 2023 Nov;
55(1):177-181.
PMID: 38018835
Background: The current fungal meningitis outbreak caused by contaminated epidural anesthesia with among patients who underwent surgical procedures in Matamoros, Mexico remains a cause of concern. Its association with an...