Pedro P C Souza
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Explore the profile of Pedro P C Souza including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
423
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0
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Recent Articles
1.
Nilsson K, Henning P, El Shahawy M, Nethander M, Andersen T, Ejersted C, et al.
Nat Commun
. 2021 Aug;
12(1):4923.
PMID: 34389713
With increasing age of the population, countries across the globe are facing a substantial increase in osteoporotic fractures. Genetic association signals for fractures have been reported at the RSPO3 locus,...
2.
Davidsen M, Teixeira J, Dehli J, Karlsson C, Kraft D, Souza P, et al.
Colloids Surf B Biointerfaces
. 2021 Aug;
207:111972.
PMID: 34364251
Polydopamine (PDA) is the final oxidation product of dopamine or other catecholamines. Since the first reports of PDA coatings starting around 2007, these coatings have been widely studied as a...
3.
Souza P, Lerner U
Front Immunol
. 2019 Aug;
10:1663.
PMID: 31379855
M-CSF and RANKL are two crucial cytokines stimulating differentiation of mature, bone resorbing, multinucleated osteoclasts from mononucleated progenitor cells in the monocyte/macrophage lineage. In addition to the receptors for M-CSF...
4.
Persson E, Souza P, Floriano-Marcelino T, Conaway H, Henning P, Lerner U
Front Immunol
. 2019 Jun;
10:1164.
PMID: 31191537
The gp130 family of cytokines signals through receptors dimerizing with the gp130 subunit. Downstream signaling typically activates STAT3 but also SHP2/Ras/MAPK pathways. Oncostatin M (OSM) is a unique cytokine in...
5.
Souza P, Lundberg P, Lundgren I, Magalhaes F, Costa-Neto C, Lerner U
Sci Rep
. 2019 Mar;
9(1):2973.
PMID: 30814538
The regulation of the kallikrein-kinin system is an important mechanism controlling vasodilation and promoting inflammation. We aimed to investigate the role of Toll-like receptor 2 (TLR2) in regulating kinin B...
6.
Mariscal-Munoz E, Costa C, Tavares H, Bianchi J, Hebling J, Machado J, et al.
Clin Oral Investig
. 2015 Jul;
20(3):503-11.
PMID: 26224513
Objectives: The aim of this study was to analyze the capacity of a new modified laser surface to stimulate calvarial osteoblasts isolated from neonatal mouse bones to differentiate and form...
7.
Kassem A, Henning P, Lundberg P, Souza P, Lindholm C, Lerner U
J Biol Chem
. 2015 Jun;
290(33):20147-58.
PMID: 26085099
Periodontitis has been associated with rheumatoid arthritis. In experimental arthritis, concomitant periodontitis caused by oral infection with Porphyromonas gingivalis enhances articular bone loss. The aim of this study was to...
8.
de Vries T, Schoenmaker T, Aerts D, Grevers L, Souza P, Nazmi K, et al.
J Cell Physiol
. 2014 Jun;
230(1):210-25.
PMID: 24962140
Osteoclasts and macrophages share progenitors that must receive decisive lineage signals driving them into their respective differentiation routes. Macrophage colony stimulation factor M-CSF is a common factor; bone is likely...
9.
Costa-Neto C, Duarte D, Lima V, Maria A, Prando E, Rodriguez D, et al.
Clin Sci (Lond)
. 2014 Feb;
126(11):753-74.
PMID: 24559183
GPCRs (G-protein-coupled receptors) are among the most important targets for drug discovery due to their ubiquitous expression and participation in cellular events under both healthy and disease conditions. These receptors...
10.
Souza P, Lerner U
Immunol Invest
. 2013 Sep;
42(7):555-622.
PMID: 24004059
Chronic inflammatory processes close to bone often lead to loss of bone in diseases such as rheumatoid arthritis, periodontitis, loosened joint prosthesis and tooth implants. This is mainly due to...