Pedro Chacon
Overview
Explore the profile of Pedro Chacon including associated specialties, affiliations and a list of published articles.
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Articles
22
Citations
256
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Recent Articles
1.
Human Neutrophils Couple Nitric Oxide Production and Extracellular Trap Formation in Allergic Asthma
Chacon P, Vega-Rioja A, Doukkali B, Del Valle Rodriguez A, Fernandez-Delgado L, Dominguez-Cereijo L, et al.
Am J Respir Crit Care Med
. 2024 Mar;
210(5):593-606.
PMID: 38445953
Nitric oxide (NO) is increased in the airways and serum of patients with allergic asthma, suggesting an important role in asthma. NO production has been widely attributed to the canonical...
2.
Lineros R, Fernandez-Delgado L, Vega-Rioja A, Chacon P, Doukkali B, Monteseirin J, et al.
Biomedicines
. 2023 May;
11(5).
PMID: 37238914
Inhaled corticosteroids (ICSs) are widely used in chronic obstructive pulmonary disease (COPD) and in combination with long-acting β2 agonists (LABAs) to reduce exacerbations and improve patient lung function and quality...
3.
Vega-Rioja A, Chacon P, Fernandez-Delgado L, Doukkali B, Del Valle Rodriguez A, Perkins J, et al.
Front Immunol
. 2022 Dec;
13:1015529.
PMID: 36518751
Background: Neutrophils are involved in the pathophysiology of allergic asthma, where the Eosinophil Cationic Protein ECP) is a critical inflammatory mediator. Although ECP production is attributed to eosinophils, we reported...
4.
Chacon P, Vega-Rioja A, Doukkali B, Del Valle Rodriguez A, Bellido V, Puente Y, et al.
FASEB J
. 2021 Mar;
35(5):e21483.
PMID: 33788304
Histamine is a critical inflammatory mediator in allergic diseases. We showed in a previous work that neutrophils from allergic patients produce histamine in response to allergens to which the patients...
5.
Alcaniz L, Vega A, Chacon P, El Bekay R, Ventura I, Aroca R, et al.
FASEB J
. 2013 Apr;
27(7):2902-10.
PMID: 23572231
Histamine is an important mediator in the development of allergic reactions. Only a small subset of human cell types is able to produce histamine. No previous studies have shown that...
6.
Ordonez P, Koriyama C, Ding S, Yoshiwara E, Corvalan A, Takano J, et al.
Anticancer Res
. 2011 Oct;
31(10):3607-13.
PMID: 21965785
Aim: To clarify the reason for the low frequency of Epstein-Barr virus-associated gastric carcinoma (EBVaGC) in Peru, despite the high frequency reported in neighboring countries, the distribution of the distinctive...
7.
Vega A, El Bekay R, Chacon P, Ventura I, Monteseirin J
Atherosclerosis
. 2009 Oct;
209(2):344-51.
PMID: 19837408
Studies indicate that both alterations in leukocyte and endothelial cell adhesion molecules and the renin angiotensin system are involved in the pathogenesis of atherosclerosis processes in human hypertension. The present...
8.
Alba G, El Bekay R, Chacon P, Reyes M, Ramos E, Olivan J, et al.
J Leukoc Biol
. 2008 Jun;
84(2):397-405.
PMID: 18515325
Angiotensin II (Ang II) is a peptide hormone able to elicit a strong production of reactive oxygen species by human neutrophils. In this work, we have addressed whether expression of...
9.
El Bekay R, Alba G, Reyes M, Chacon P, Vega A, Martin-Nieto J, et al.
J Mol Endocrinol
. 2007 Nov;
39(5):351-63.
PMID: 17975262
Angiotensin II (Ang II) highly stimulates superoxide anion production by neutrophils. The G-protein Rac2 modulates the activity of NADPH oxidase in response to various stimuli. Here, we describe that Ang...
10.
Monteseirin J, Vega A, Chacon P, Camacho M, El Bekay R, Asturias J, et al.
J Immunol
. 2007 Aug;
179(4):2634-41.
PMID: 17675527
The production of eosinophil cationic protein (ECP) in IgE-mediated diseases has been associated mainly with eosinophils, although no IgE-dependent ECP release has been observed in these cells. Because there is...