Jose Martin-Nieto
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Explore the profile of Jose Martin-Nieto including associated specialties, affiliations and a list of published articles.
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37
Citations
663
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Recent Articles
1.
Larriba E, de Juan Romero C, Garcia-Martinez A, Quintanar T, Rodriguez-Lescure A, Soto J, et al.
Comput Biol Med
. 2024 Jul;
179:108833.
PMID: 38981212
This study provides a comprehensive perspective on the deregulated pathways and impaired biological functions prevalent in human glioblastoma (GBM). In order to characterize differences in gene expression between individuals diagnosed...
2.
Quereda C, Pastor A, Martin-Nieto J
Cancer Cell Int
. 2022 Dec;
22(1):395.
PMID: 36494657
Dystroglycan (DG) is a glycoprotein composed of two subunits that remain non-covalently bound at the plasma membrane: α-DG, which is extracellular and heavily O-mannosyl glycosylated, and β-DG, an integral transmembrane...
3.
Uribe M, Martin-Nieto J, Quereda C, Rubio-Fernandez M, Cruces J, Janssen G, et al.
J Proteome Res
. 2021 May;
20(6):3268-3277.
PMID: 34027671
Mutations in the 1 gene, encoding a protein -mannosyltransferase essential for α-dystroglycan (α-DG) glycosylation, are frequently observed in a group of rare congenital muscular dystrophies, collectively known as dystroglycanopathies. However,...
4.
Fuentes-Baile M, Ventero M, Encinar J, Garcia-Morales P, Poveda-Deltell M, Perez-Valenciano E, et al.
Cancers (Basel)
. 2020 Dec;
12(12).
PMID: 33322337
We have determined the effects of the IGF-1R tyrosine kinase inhibitors BMS-754807 (BMS) and OSI-906 (OSI) on cell proliferation and cell-cycle phase distribution in human colon, pancreatic carcinoma, and glioblastoma...
5.
Martin-Nieto J, Uribe M, Esteve-Rudd J, Herrero M, Campello L
Neurosci Lett
. 2019 Jul;
708:134361.
PMID: 31276729
We have previously reported the expression of Parkinson disease-associated genes encoding α-synuclein, parkin and UCH-L1 in the retina across mammals. DJ-1, or parkinsonism-associated deglycase, is a redox-sensitive protein with putative...
6.
Rubio-Fernandez M, Uribe M, Vicente-Tejedor J, Germain F, Susin-Lara C, Quereda C, et al.
Sci Rep
. 2018 Jun;
8(1):8543.
PMID: 29867208
Hypoglycosylation of α-dystroglycan (α-DG) resulting from deficiency of protein O-mannosyltransferase 1 (POMT1) may cause severe neuromuscular dystrophies with brain and eye anomalies, named dystroglycanopathies. The retinal involvement of these disorders...
7.
Haro C, Uribe M, Quereda C, Cruces J, Martin-Nieto J
Mol Vis
. 2018 Feb;
24:43-58.
PMID: 29416295
Purpose: Dystroglycanopathies are a heterogeneous group of recessive neuromuscular dystrophies that affect the muscle, brain and retina, and are caused by deficiencies in the O-glycosylation of α-dystroglycan. This post-translational modification...
8.
Uribe M, Haro C, Ventero M, Campello L, Cruces J, Martin-Nieto J
Mol Vis
. 2016 Jul;
22:658-73.
PMID: 27375352
Purpose: The POMGNT1 gene, encoding protein O-linked-mannose β-1,2-N-acetylglucosaminyltransferase 1, is associated with muscle-eye-brain disease (MEB) and other dystroglycanopathies. This gene's lack of function or expression causes hypoglycosylation of α-dystroglycan (α-DG)...
9.
Reyes-Quiroz M, Alba G, Saenz J, Geniz I, Jimenez J, Martin-Nieto J, et al.
Int Immunopharmacol
. 2016 Jun;
38:357-66.
PMID: 27351826
Liver X receptors (LXRs) are ligand-activated nuclear receptors involved mainly in the regulation of cholesterol metabolism in many organs, including liver and intestine, as well as in macrophages and neutrophils....
10.
Alba G, Reyes-Quiroz M, Saenz J, Geniz I, Jimenez J, Martin-Nieto J, et al.
Eur J Nutr
. 2015 Dec;
55(8):2485-2492.
PMID: 26715521
Purpose: Oxysterols are cholesterol-oxygenated derivatives generated in the organism and also present in foods because of cholesterol oxidation during processing and storage. They are the natural ligands of liver X...