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Pawel Sachadyn

Explore the profile of Pawel Sachadyn including associated specialties, affiliations and a list of published articles. Areas
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Articles 40
Citations 301
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Recent Articles
1.
Mania S, Banach-Kopec A, Maciejewska N, Czerwiec K, Slonimska P, Deptula M, et al.
Molecules . 2024 Oct; 29(19). PMID: 39407579
This study presents an innovative method for producing thermosensitive bioink from chitosan hydrogels saturated with carbon dioxide and agarose. It focuses on a detailed characterisation of their physicochemical properties and...
2.
Schumacher A, Mucha P, Puchalska I, Deptula M, Wardowska A, Tyminska A, et al.
Biomed Pharmacother . 2024 Jun; 177:117052. PMID: 38943988
Adipose-derived mesenchymal stromal cells (AD-MSCs) are an essential issue in modern medicine. Extensive preclinical and clinical studies have shown that mesenchymal stromal/stem cells, including AD-MSCs, have specific properties (ability to...
3.
Slonimska P, Sachadyn P, Zielinski J, Skrzypski M, Pikula M
Adv Wound Care (New Rochelle) . 2024 Jan; 13(4):187-199. PMID: 38183626
Chemotherapy is a primary method to treat cancer. While chemotherapeutic drugs are designed to target rapidly dividing cancer cells, they can also affect other cell types. In the case of...
4.
Dzierzynska M, Sawicka J, Deptula M, Sosnowski P, Sass P, Peplinska B, et al.
Sci Rep . 2023 Apr; 13(1):6273. PMID: 37072464
Self-assembling peptides can be used for the regeneration of severely damaged skin. They can act as scaffolds for skin cells and as a reservoir of active compounds, to accelerate scarless...
5.
Sosnowski P, Sass P, Stanislawska-Sachadyn A, Krzeminski M, Sachadyn P
Biomed Pharmacother . 2023 Feb; 160:114317. PMID: 36736277
Despite the animal models' complexity, researchers tend to reduce the number of animals in experiments for expenses and ethical concerns. This tendency makes the risk of false-positive results, as statistical...
6.
Sass P, Sosnowski P, Kaminska J, Deptula M, Skoniecka A, Zielinski J, et al.
J Tissue Eng Regen Med . 2022 Nov; 16(12):1238-1248. PMID: 36350668
DNA methyltransferase inhibitor zebularine was proven to induce regeneration in the ear pinna in mice. We utilized a dorsal skin wound model to further evaluate this epigenetic inhibitor in wound...
7.
Sosnowski P, Sass P, Slonimska P, Platek R, Kaminska J, Baczynski Keller J, et al.
Pharmaceuticals (Basel) . 2022 May; 15(5). PMID: 35631437
The ear pinna is a complex tissue consisting of the dermis, cartilage, muscles, vessels, and nerves. Ear pinna healing is a model of regeneration in mammals. In some mammals, including...
8.
Mazuryk J, Puchalska I, Kozinski K, Slusarz M, Ruczynski J, Rekowski P, et al.
Int J Mol Sci . 2021 Jul; 22(11). PMID: 34200045
Ischemic stroke is a disturbance in cerebral blood flow caused by brain tissue ischemia and hypoxia. We optimized a multifactorial in vitro model of acute ischemic stroke using rat primary...
9.
Sawicka J, Ilowska E, Deptula M, Sosnowski P, Sass P, Czerwiec K, et al.
Int J Mol Sci . 2021 Apr; 22(8). PMID: 33917000
Technological developments in the field of biologically active peptide applications in medicine have increased the need for new methods for peptide delivery. The disadvantage of peptides as drugs is their...
10.
Deptula M, Karpowicz P, Wardowska A, Sass P, Sosnowski P, Mieczkowska A, et al.
Adv Wound Care (New Rochelle) . 2020 Oct; 9(12):657-675. PMID: 33124966
This study evaluated the use of novel peptides derived from platelet-derived growth factor (PDGF-BB) as potential wound healing stimulants. One of the compounds (named PDGF2) was subjected for further research...