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Pavol Genzor

Explore the profile of Pavol Genzor including associated specialties, affiliations and a list of published articles. Areas
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Articles 17
Citations 321
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Recent Articles
1.
Vashi B, Pettrone K, Wilson C, Chenoweth J, Brandsma J, Gregory M, et al.
PLoS One . 2025 Feb; 20(2):e0314518. PMID: 39982872
Introduction: With the emergence of new SARS-CoV-2 variants has come significant variations in disease manifestation, severity, and duration in non-hospitalized infected patients. To characterize symptom patterns and risk factors associated...
2.
Rouse M, Gann E, Brandsma J, Sugiharto V, Robertson H, Genzor P, et al.
Blood Purif . 2024 Dec; 1-11. PMID: 39662058
Introduction: We report an Intervention/outcome study of 33 severe COVID-19 subjects who received Seraph 100 Microbind Affinity Blood Filter (Seraph 100) hemoperfusion therapy (15 survivors, 18 non-survivors) under emergency authorization...
3.
Chenoweth J, Brandsma J, Striegel D, Genzor P, Chiyka E, Blair P, et al.
Commun Med (Lond) . 2024 Jun; 4(1):120. PMID: 38890515
Background: Sepsis from infection is a global health priority and clinical trials have failed to deliver effective therapeutic interventions. To address complicating heterogeneity in sepsis pathobiology, and improve outcomes, promising...
4.
Chenoweth J, Colantuoni C, Striegel D, Genzor P, Brandsma J, Blair P, et al.
Nat Commun . 2024 May; 15(1):4606. PMID: 38816375
Our limited understanding of the pathophysiological mechanisms that operate during sepsis is an obstacle to rational treatment and clinical trial design. There is a critical lack of data from low-...
5.
Wilson C, Vashi B, Genzor P, Gregory M, Yau J, Wolfe L, et al.
SLAS Technol . 2023 Oct; 28(6):442-448. PMID: 37844868
Rapid and accurate measurements of immune protein markers are essential for diagnosis and treatment in all clinical settings. The recent pandemic has revealed a stark need for developing new tools...
6.
Luo W, Hickman A, Genzor P, Ghirlando R, Furman C, Menshikh A, et al.
Nucleic Acids Res . 2022 Dec; 50(22):13128-13142. PMID: 36537219
DNA transposon systems are widely used in mammalian cells for genetic modification experiments, but their regulation remains poorly understood. We used biochemical and cell-based assays together with AlphaFold modeling and...
7.
Khateb M, Perovanovic J, Ko K, Jiang K, Feng X, Acevedo-Luna N, et al.
Cell Rep . 2022 Aug; 40(7):111219. PMID: 35977485
Embryonic stem cells (ESCs) can adopt lineage-specific gene-expression programs by stepwise exposure to defined factors, resulting in the generation of functional cell types. Bulk and single-cell-based assays were employed to...
8.
Stoyko D, Genzor P, Haase A
iScience . 2022 Jun; 25(6):104427. PMID: 35669519
PIWI-interacting RNAs (piRNAs) guard germline genomes against the deleterious action of mobile genetic elements. PiRNAs use extensive base-pairing to recognize their targets and variable 3'ends could change the specificity and...
9.
Meng Q, Stoyko D, Andrews C, Konstantinidou P, Genzor P, O T, et al.
Nucleic Acids Res . 2022 May; 50(15):e90. PMID: 35639929
The combination of genome-editing and epitope tagging provides a powerful strategy to study proteins with high affinity and specificity while preserving their physiological expression patterns. However, stably modifying endogenous genes...
10.
Genzor P, Konstantinidou P, Stoyko D, Manzourolajdad A, Andrews C, Elchert A, et al.
Genome Res . 2021 Oct; 31(11):2058-2068. PMID: 34667116
Defense against genome invaders universally relies on RNA-guided immunity. Prokaryotic CRISPR-Cas and eukaryotic RNA interference pathways recognize targets by complementary base-pairing, which places the sequences of their guide RNAs at...