Pavel Krcmar
Overview
Explore the profile of Pavel Krcmar including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
21
Citations
172
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Strapacova S, Brenerova P, Krcmar P, Andersson P, van Ede K, van Duursen M, et al.
Toxicology
. 2018 May;
404-405:33-41.
PMID: 29738842
Toxicity of dioxin-like compounds (DLCs), such as polychlorinated dibenzo-p-dioxins, dibenzofurans and biphenyls, is largely mediated via aryl hydrocarbon receptor (AhR) activation. AhR-mediated gene expression can be tissue-specific; however, the inducibility...
2.
Tylichova Z, Slavik J, Ciganek M, Ovesna P, Krcmar P, Strakova N, et al.
J Cell Biochem
. 2017 Dec;
119(6):4664-4679.
PMID: 29274292
Docosahexaenoic acid (DHA) and sodium butyrate (NaBt) exhibit a number of interactive effects on colon cancer cell growth, differentiation, or apoptosis; however, the molecular mechanisms responsible for these interactions and...
3.
Faust D, Vondracek J, Krcmar P, Smerdova L, Prochazkova J, Hruba E, et al.
Arch Toxicol
. 2012 Dec;
87(4):681-98.
PMID: 23196670
Although the tumor-promoting effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), coplanar polychlorinated biphenyls (PCBs), and related compounds in liver tissue are primarily attributed to the activation of the aryl hydrocarbon receptor (AhR), the...
4.
Valovicova Z, Mesarosova M, Trilecova L, Hruba E, Marvanova S, Krcmar P, et al.
Mutat Res
. 2012 Feb;
743(1-2):91-8.
PMID: 22306306
Differences between tissues in the expression of drug-metabolizing enzymes may substantially contribute to tissue-specificity of chemical carcinogens. To verify this hypothesis, the spontaneously immortalized human keratinocytes HaCaT were used, in...
5.
Gabelova A, Valovicova Z, Mesarosova M, Trilecova L, Hruba E, Marvanova S, et al.
Environ Mol Mutagen
. 2011 Aug;
52(8):636-45.
PMID: 21809388
The goal of this study was to investigate the genotoxicity of 7H-dibenzo[c,g]carbazole (DBC), a ubiquitous environmental pollutant, and its methyl derivatives, 5,9-dimethylDBC (DiMeDBC), a strict hepatocarcinogen, and N-methylDBC (N-MeDBC), a...
6.
Umannova L, Machala M, Topinka J, Schmuczerova J, Krcmar P, Neca J, et al.
Toxicol Lett
. 2011 Jul;
206(2):121-9.
PMID: 21745554
Alveolar type II epithelial (AEII) cells regulate lung inflammatory response and, simultaneously, they are a target of environmental carcinogenic factors. We employed an in vitro model of rat AEII cells,...
7.
Trilecova L, Krckova S, Marvanova S, Pencikova K, Krcmar P, Neca J, et al.
Chem Res Toxicol
. 2011 May;
24(6):866-76.
PMID: 21604763
The methylated benzo[a]pyrenes (MeBaPs) are present at significant levels in the environment, especially in the sediments contaminated by petrogenic PAHs. However, the existing data on their toxic effects in vitro...
8.
Hruba E, Trilecova L, Marvanova S, Krcmar P, Vykopalova L, Milcova A, et al.
Toxicol Lett
. 2010 Jun;
197(3):227-35.
PMID: 20542099
Exposure to polycyclic aromatic hydrocarbons (PAHs) has been positively associated with prostate cancer, but knowledge of the formation of PAH-DNA adducts and related genotoxic events in prostatic cells is limited....
9.
Vondracek J, Krcmar P, Prochazkova J, Trilecova L, Gavelova M, Skalova L, et al.
Chem Biol Interact
. 2009 Jun;
180(2):226-37.
PMID: 19497421
In contrast to hepatocytes, there is only limited information about the expression and activities of enzymes participating in metabolic activation of environmental mutagens, including polycyclic aromatic hydrocarbons (PAHs), in liver...
10.
Lincova E, Hampl A, Pernicova Z, Starsichova A, Krcmar P, Machala M, et al.
Biochem Pharmacol
. 2009 May;
78(6):561-72.
PMID: 19433066
Antitumorigenic effects of non-steroidal anti-inflammatory drugs (NSAIDs) are well established in several types of cancer disease. However, the mechanisms driving these processes are not understood in all details. In our...