Pavel Filipcik
Overview
Explore the profile of Pavel Filipcik including associated specialties, affiliations and a list of published articles.
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6
Citations
176
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0
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Recent Articles
1.
Burgess A, Loughran T, Turk L, Nyvall H, Dunlop J, Jamieson S, et al.
Sci Adv
. 2025 Feb;
11(9):eadq4187.
PMID: 40009677
Transcription factor ubiquitination is a decisive regulator of growth and development. The DET1-DDB1-DDA1 (DDD) complex associates with the Cullin-4 ubiquitin ligase (CRL4) and a second ubiquitin ligase, COP1, to control...
2.
Matinyan S, Filipcik P, Abrahams J
Acta Crystallogr A Found Adv
. 2024 Jan;
80(Pt 1):1-17.
PMID: 38189437
Deep learning techniques can recognize complex patterns in noisy, multidimensional data. In recent years, researchers have started to explore the potential of deep learning in the field of structural biology,...
3.
Matinyan S, Demir B, Filipcik P, Abrahams J, Van Genderen E
Acta Crystallogr A Found Adv
. 2023 Jun;
79(Pt 4):360-368.
PMID: 37338216
As an alternative approach to X-ray crystallography and single-particle cryo-electron microscopy, single-molecule electron diffraction has a better signal-to-noise ratio and the potential to increase the resolution of protein models. This...
4.
Bae M, Cassilly C, Liu X, Park S, Tusi B, Chen X, et al.
Nature
. 2022 Jul;
608(7921):168-173.
PMID: 35896748
Multiple studies have established associations between human gut bacteria and host physiology, but determining the molecular mechanisms underlying these associations has been challenging. Akkermansia muciniphila has been robustly associated with...
5.
Filipcik P, Latham S, Cadell A, Day C, Croucher D, Mace P
Proc Natl Acad Sci U S A
. 2020 Aug;
117(35):21308-21318.
PMID: 32817551
The MEKK1 protein is a pivotal kinase activator of responses to cellular stress. Activation of MEKK1 can trigger various responses, including mitogen-activated protein (MAP) kinases, NF-κB signaling, or cell migration....
6.
Filipcik P, Curry J, Mace P
J Mol Biol
. 2017 Feb;
429(8):1097-1113.
PMID: 28235544
Phosphorylation and ubiquitination are pervasive post-translational modifications that impact all processes inside eukaryotic cells. The role of each modification has been studied for decades, and functional interplay between the two...
7.
Gibadulinova A, Pastorek M, Filipcik P, Radvak P, Csaderova L, Vojtesek B, et al.
Oncotarget
. 2016 Mar;
7(16):22508-22.
PMID: 26967060
S100P belongs to the S100 family of calcium-binding proteins regulating diverse cellular processes. Certain S100 family members (S100A4 and S100B) are associated with cancer and used as biomarkers of metastatic...