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Pavan Vaddady

Explore the profile of Pavan Vaddady including associated specialties, affiliations and a list of published articles. Areas
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Articles 14
Citations 24
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Recent Articles
11.
Vaddady P, Kandala B, Yee K
Antimicrob Agents Chemother . 2020 Sep; 64(11). PMID: 32868326
Doravirine is a non-nucleoside reverse transcriptase inhibitor for treatment of human immunodeficiency virus type 1 (HIV-1) infection. A population pharmacokinetic (PK) model for treatment-naive participants in doravirine clinical studies was...
12.
Greaves W, Wan H, Yee K, Kandala B, Vaddady P, Hwang C
Antimicrob Agents Chemother . 2019 Sep; 63(12). PMID: 31548188
Doravirine is a non-nucleoside reverse transcriptase inhibitor approved for the treatment of HIV-1. In a phase 1 trial, doravirine exposure was transiently decreased when treatment was started immediately after stopping...
13.
Feng H, Guo Z, Caro L, Marshall W, Liu F, Panebianco D, et al.
Clin Transl Sci . 2018 Jul; 11(6):553-561. PMID: 30040872
We conducted two phase I trials to evaluate the pharmacokinetic interactions between elbasvir (EBR), grazoprevir (GZR), and methadone (MK-8742-P010 and MK-5172-P030) in non-hepatitis C virus (HCV)-infected participants on methadone maintenance...
14.
Feng H, Guo Z, Caro L, Marshall W, Liu F, Panebianco D, et al.
Clin Transl Sci . 2018 Jul; 11(6):562-572. PMID: 30040871
The aims of these phase I trials were to evaluate the pharmacokinetic interaction between elbasvir (EBR) or grazoprevir (GZR) and buprenorphine/naloxone (BUP/NAL). Trial 1 was a single-dose trial in healthy...