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Paulo Sergio Lopes de Oliveira

Explore the profile of Paulo Sergio Lopes de Oliveira including associated specialties, affiliations and a list of published articles. Areas
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Articles 24
Citations 215
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Recent Articles
1.
Avelino T, Provencio M, Peroni L, Domingues R, Torres F, de Oliveira P, et al.
PLoS One . 2024 May; 19(5):e0303612. PMID: 38820505
Obesity, a burgeoning global health crisis, has tripled in prevalence over the past 45 years, necessitating innovative research methodologies. Adipocytes, which are responsible for energy storage, play a central role...
2.
Pramio D, Vieceli F, Varella-Branco E, Goes C, Kobayashi G, da Silva Pelegrina D, et al.
Biochim Biophys Acta Gene Regul Mech . 2023 Jan; 1866(1):194909. PMID: 36682583
Protein kinase M zeta, PKMζ, is a brain enriched kinase with a well characterized role in Long-Term Potentiation (LTP), the activity-dependent strengthening of synapses involved in long-term memory formation. However,...
3.
de Castro Fonseca M, de Oliveira J, Araujo B, Canateli C, do Prado P, Amorim Neto D, et al.
iScience . 2021 Aug; 24(8):102841. PMID: 34381968
Current studies estimate that 1-3% of females with unexplained intellectual disability (ID) present splice site, nonsense, frameshift, or missense mutations in the DDX3X protein (DEAD-Box Helicase 3 X-Linked). However, the...
4.
Guerra J, de Sa Pereira B, da Cruz J, Scherer N, Furtado C, Montalvao De Azevedo R, et al.
Cells . 2019 Aug; 8(8). PMID: 31426508
To identify underlying mechanisms involved with metastasis formation in Wilms tumors (WTs), we performed comprehensive DNA methylation and gene expression analyses of matched normal kidney (NK), WT blastemal component, and...
5.
de Oliveira J, do Prado P, da Costa S, Sforca M, Canateli C, Ranzani A, et al.
Nat Chem Biol . 2018 Dec; 15(1):62-70. PMID: 30531907
Ubiquitin-conjugating enzymes (E2) enable protein ubiquitination by conjugating ubiquitin to their catalytic cysteine for subsequent transfer to a target lysine side chain. Deprotonation of the incoming lysine enables its nucleophilicity,...
6.
de Guzzi Cassago C, Dias M, Pinheiro M, Pasquali C, Bastos A, Islam Z, et al.
Biochemistry . 2018 Oct; 57(44):6293-6307. PMID: 30295466
Phosphate-activated glutaminases catalyze the deamidation of glutamine to glutamate and play key roles in several physiological and pathological processes. In humans, GLS encodes two multidomain splicing isoforms: KGA and GAC....
7.
Santos C, de Giuseppe P, de Souza F, Zanphorlin L, Domingues M, Pirolla R, et al.
Biotechnol Biofuels . 2018 Aug; 11:223. PMID: 30127853
Background: Arabinoxylan is an abundant polysaccharide in industrially relevant biomasses such as sugarcane, corn stover and grasses. However, the arabinofuranosyl di-substitutions that decorate the xylan backbone are recalcitrant to most...
8.
Domingues M, Souza F, Vieira P, de Morais M, Zanphorlin L, Santos C, et al.
J Biol Chem . 2018 Jul; 293(35):13636-13649. PMID: 29997257
The classical microbial strategy for depolymerization of β-mannan polysaccharides involves the synergistic action of at least two enzymes, endo-1,4-β-mannanases and β-mannosidases. In this work, we describe the first exo-β-mannanase from...
9.
de Vasconcelos T, Ribeiro-Filho H, Lahlou S, Pereira J, de Oliveira P, Magalhaes P
Eur J Pharmacol . 2018 May; 830:105-114. PMID: 29709439
Compounds containing a nitro group may reveal vasodilator properties. Several nitro compounds have a NO group in a short aliphatic chain connected to an aromatic group. In this study, we...
10.
Filho H, Videira N, Bridi A, Tittanegro T, Helena Batista F, Pereira J, et al.
Front Endocrinol (Lausanne) . 2018 Feb; 9:11. PMID: 29449830
Peroxisome proliferator-activated receptor gamma (PPARγ) is a member of a nuclear receptor superfamily and acts as a ligand-dependent transcription factor, playing key roles in maintenance of adipose tissue and in...