Paulo Cesar Ghedini
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Explore the profile of Paulo Cesar Ghedini including associated specialties, affiliations and a list of published articles.
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Articles
35
Citations
156
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Recent Articles
11.
Moreira L, Turones L, Campos H, Nazareth A, Thomaz D, Gil E, et al.
Life Sci
. 2022 Nov;
312:121199.
PMID: 36402170
Aims: Oxidative stress, impaired antioxidant defense and neuroinflammation are often associated with the onset and progression of neuropsychiatric diseases. Conversely, several piperazine compounds presents beneficial neuropharmacological effects as well as...
12.
Campos H, da Costa M, Moreira L, da Silva Neri H, Branco da Silva C, Pruccoli L, et al.
Toxicology
. 2021 Nov;
465:153033.
PMID: 34774662
Chronic exposure to aluminium (Al) can contribute to the progression of several neurological and neurodegenerative diseases. Al is a metal that promotes oxidative damage leading to neuronal death in different...
13.
de Jesus E, Nunes A, Pontes C, Macedo L, Mendes E, Ianzer D, et al.
Clin Exp Pharmacol Physiol
. 2021 Aug;
48(12):1693-1703.
PMID: 34427931
The proline-rich oligopeptide from Bothrops jararaca snake venom, Bj-PRO-7a, promotes acute effects in blood pressure in hypertensive animals. However, the cardiac effects of this heptapeptide are completely unknown. Thus, we...
14.
Moreira L, Brito A, da Silva D, Siqueira L, Bueno da Silva D, Cardoso C, et al.
Behav Brain Res
. 2020 Dec;
401:113066.
PMID: 33333109
Major depression disorder (MDD) is one of the most widespread and debilitating psychiatric diseases and may be associated with other mental disorders such as anxiety. Despite advances in neurobiology studies,...
15.
da Silva Lima D, da Silva Gomes L, de Sousa Figueredo E, de Godoi M, Silva E, da Silva Neri H, et al.
Exp Mol Pathol
. 2020 Jun;
116:104486.
PMID: 32585149
Since the industrial revolution, all living beings have become susceptible to numerous sources of aluminum (Al) exposure. In addition to causing proven toxicity in many organs and systems, Al can...
16.
Bernini de Brito R, Ghedini P
Heliyon
. 2020 Jun;
6(5):e04015.
PMID: 32509985
Escitalopram (ESC), a selective serotonin reuptake inhibitor indicated for the treatment of depression and anxiety disorders, is primarily metabolized by cytochrome P450 (CYP) 2C19, which is a highly polymorphic enzyme...
17.
da Silva Gomes L, da Silva Lima D, Costa J, Branco da Silva C, Marques M, Brito P, et al.
J Trace Elem Med Biol
. 2020 Jun;
61:126559.
PMID: 32485499
Backgroung: Exposure to environmental pollutants in critical developmental windows may predispose the prostate to permanent changes in its homeostasis. Thus, it is essential to know the effects that environmental toxics,...
18.
Rodrigues-Silva C, Semedo A, da Silva Neri H, Vianello R, Galaviz-Hernandez C, Sosa-Macias M, et al.
Neuropsychiatr Dis Treat
. 2020 Feb;
16:427-432.
PMID: 32103962
Introduction: Clozapine (CLZ) is the gold standard drug for treatment-refractory schizophrenia (TRS). However, approximately 30% of patients partially respond to CLZ, defining this subset with super refractory schizophrenia (SRS). Alterations...
19.
Silva J, Ramos J, Campos M, da Silva Lima D, Brito P, Mendes E, et al.
Reprod Toxicol
. 2019 Mar;
85:83-92.
PMID: 30822521
This study evaluated the effects of BPS (40 μg/kg/day, during 28 consecutive days) on the male ventral prostate and female prostate of adult gerbils. For comparative purposes, gerbils were also...
20.
de Oliveira T, Thomaz D, da Silva Neri H, Cerqueira L, Garcia L, Vicente Gil H, et al.
Oxid Med Cell Longev
. 2018 Nov;
2018:9842908.
PMID: 30420910
Pequi () is an endemic species from Brazilian Cerrado, and their fruits are widely used in regional cuisine. In this work, a crude hydroalcoholic extract (CHE) of leaves and its...