Pauline Depuydt
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Explore the profile of Pauline Depuydt including associated specialties, affiliations and a list of published articles.
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5
Citations
136
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Recent Articles
1.
Decaesteker B, Denecker G, Van Neste C, Dolman E, Van Loocke W, Gartlgruber M, et al.
Nat Commun
. 2018 Nov;
9(1):4866.
PMID: 30451831
Chromosome 17q gains are almost invariably present in high-risk neuroblastoma cases. Here, we perform an integrative epigenomics search for dosage-sensitive transcription factors on 17q marked by H3K27ac defined super-enhancers and...
2.
Depuydt P, Koster J, Boeva V, Hocking T, Speleman F, Schleiermacher G, et al.
Sci Data
. 2018 Oct;
5:180240.
PMID: 30375995
Neuroblastoma, a pediatric tumor of the sympathetic nervous system, is predominantly driven by copy number aberrations, which predict survival outcome in global neuroblastoma cohorts and in low-risk cases. For high-risk...
3.
Depuydt P, Boeva V, Hocking T, Cannoodt R, Ambros I, Ambros P, et al.
J Natl Cancer Inst
. 2018 Mar;
110(10):1084-1093.
PMID: 29514301
Background: Neuroblastoma is characterized by substantial clinical heterogeneity. Despite intensive treatment, the survival rates of high-risk neuroblastoma patients are still disappointingly low. Somatic chromosomal copy number aberrations have been shown...
4.
De Wilde B, Beckers A, Lindner S, Kristina A, De Preter K, Depuydt P, et al.
Oncotarget
. 2018 Mar;
9(9):8334-8349.
PMID: 29492199
Genetically engineered mouse models have proven to be essential tools for unraveling fundamental aspects of cancer biology and for testing novel therapeutic strategies. To optimally serve these goals, it is...
5.
Bogaert D, De Bruyne M, Debacker V, Depuydt P, De Preter K, Bonroy C, et al.
Haematologica
. 2016 Sep;
102(1):192-202.
PMID: 27634199
The etiology of primary antibody deficiencies is largely unknown. Beside rare monogenic forms, the majority of cases seem to have a more complex genetic basis. Whereas common variable immunodeficiency has...