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Pauline Chenuet

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Citations 348
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Recent Articles
1.
Chenuet P, Marquant Q, Fauconnier L, Youness A, Mellier M, Marchiol T, et al.
Allergy . 2022 May; 77(11):3320-3336. PMID: 35615773
Background: Inflammasomes are large protein complexes that assemble in the cytosol in response to danger such as tissue damage or infection. Following activation, inflammasomes trigger cell death and the release...
2.
Dalloul Z, Best M, Chenuet P, Dalloul I, Le Noir S, Togbe D, et al.
Clin Transl Immunology . 2021 Jun; 10(6):e1280. PMID: 34136216
Objectives: Inhibitors of bromodomain and extra terminal domain (BET) proteins are a new and growing class of anti-cancer drugs, which decrease oncogene expression by targeting superenhancers. Antibody production is another...
3.
Di Domizio J, Belkhodja C, Chenuet P, Fries A, Murray T, Mondejar P, et al.
Nat Immunol . 2020 Jul; 21(9):1034-1045. PMID: 32661363
Skin wounds heal by coordinated induction of inflammation and tissue repair, but the initiating events are poorly defined. Here we uncover a fundamental role of commensal skin microbiota in this...
4.
Floris I, Chenuet P, Togbe D, Volteau C, Lejeune B
Dose Response . 2020 Apr; 18(1):1559325820914092. PMID: 32269504
In this study, we evaluated the efficacy of a micro-immunotherapy medicine (MIM), 2LALERG, in a preclinical model of allergic respiratory disease sensitized with birch pollen extract (BPE). BALB/c mice were...
5.
Benmerzoug S, Rose S, Bounab B, Gosset D, Duneau L, Chenuet P, et al.
Nat Commun . 2018 Dec; 9(1):5226. PMID: 30523277
Silica particles induce lung inflammation and fibrosis. Here we show that stimulator of interferon genes (STING) is essential for silica-induced lung inflammation. In mice, silica induces lung cell death and...
6.
Dalloul Z, Chenuet P, Dalloul I, Boyer F, Aldigier J, Laffleur B, et al.
J Allergy Clin Immunol . 2018 Jun; 142(4):1352-1355. PMID: 29935221
No abstract available.
7.
Chenuet P, Fauconnier L, Madouri F, Marchiol T, Rouxel N, Ledru A, et al.
Clin Sci (Lond) . 2017 Oct; 131(20):2533-2548. PMID: 29026003
T helper (Th)17 immune response participates in allergic lung inflammation and asthma is reduced in the absence of interleukin (IL)-17 in mice. Since IL-17A and IL-17F are induced and bind...
8.
Madouri F, Chenuet P, Beuraud C, Fauconnier L, Marchiol T, Rouxel N, et al.
J Allergy Clin Immunol . 2016 Oct; 139(5):1650-1666. PMID: 27746240
Background: Protein kinase C (PKC) θ, a serine/threonine kinase, is involved in T2 cell activation and proliferation. Type 2 innate lymphoid cells (ILC2s) resemble T2 cells and produce the T2...
9.
Agoro R, Piotet-Morin J, Palomo J, Michaudel C, Vigne S, Maillet I, et al.
Eur J Immunol . 2016 Aug; 46(11):2531-2541. PMID: 27569535
Allergic asthma is characterized by a strong Th2 response with inflammatory cell recruitment and structural changes in the lung. Papain is a protease allergen disrupting the airway epithelium triggering a...
10.
Michaudel C, Couturier-Maillard A, Chenuet P, Maillet I, Mura C, Couillin I, et al.
Am J Clin Exp Immunol . 2016 May; 5(1):33-40. PMID: 27168953
Exposure to ambient ozone causes airway hyperreactivity and lung inflammation, which represent an important health concern in humans. Recent clinical and experimental studies contributed to the understanding of the mechanisms...