Lionel Apetoh
Overview
Explore the profile of Lionel Apetoh including associated specialties, affiliations and a list of published articles.
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Articles
117
Citations
16778
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Recent Articles
1.
Zhang H, Madi A, Yosef N, Chihara N, Awasthi A, Pot C, et al.
Cell Rep
. 2025 Mar;
44(3):115455.
PMID: 40057956
No abstract available.
2.
Alzeeb G, Tortorelli C, Taleb J, De Luca F, Berge B, Bardet C, et al.
Front Oncol
. 2024 Aug;
14:1427428.
PMID: 39114302
Colorectal cancer (CRC) remains a significant global health burden, emphasizing the need for innovative treatment strategies. 95% of the CRC population are microsatellite stable (MSS), insensitive to classical immunotherapies such...
3.
Vidana Gamage H, Albright S, Smith A, Farmer R, Shahoei S, Wang Y, et al.
Cancer Lett
. 2024 Jun;
597:217086.
PMID: 38944231
Immune checkpoint blockade (ICB) has had limited utility in several solid tumors such as breast cancer, a major cause of cancer-related mortality in women. Therefore, there is considerable interest in...
4.
Vidana Gamage H, Shahoei S, Wang Y, Jacquin E, Weisser E, Bautista R, et al.
Cancer Lett
. 2024 Jun;
597:217042.
PMID: 38908543
Although survival from breast cancer has dramatically increased, many will develop recurrent, metastatic disease. Unfortunately, survival for this stage of disease remains very low. Activating the immune system has incredible...
5.
6.
Nascimento M, Huot-Marchand S, Fanny M, Straube M, Le Bert M, Savigny F, et al.
Front Immunol
. 2023 Dec;
14:1224383.
PMID: 38146368
Chronic obstructive pulmonary disease (COPD) is a major health issue primarily caused by cigarette smoke (CS) and characterized by breathlessness and repeated airway inflammation. NLRP6 is a cytosolic innate receptor...
7.
Richter F, Paget C, Apetoh L
Cell Stress
. 2023 Nov;
7(11):95-104.
PMID: 37970489
Adoptive cell therapy (ACT) can successfully treat hematopoietic cancers but lacks efficacy against solid tumors. This is due to insufficient T cell infiltration, high tumor heterogeneity, frequent antigen loss with...
8.
Vidana Gamage H, Shahoei S, Albright S, Wang Y, Smith A, Farmer R, et al.
bioRxiv
. 2023 Aug;
PMID: 37645737
Immune checkpoint blockade (ICB) has revolutionized cancer therapy but has had limited utility in several solid tumors such as breast cancer, a major cause of cancer-related mortality in women. Therefore,...
9.
Bod L, Kye Y, Shi J, Torlai Triglia E, Schnell A, Fessler J, et al.
Nature
. 2023 Jun;
619(7969):348-356.
PMID: 37344597
The role of B cells in anti-tumour immunity is still debated and, accordingly, immunotherapies have focused on targeting T and natural killer cells to inhibit tumour growth. Here, using high-throughput...
10.
Vinokurova D, Apetoh L
Biomolecules
. 2023 May;
13(4).
PMID: 37189417
PD-1 blockade rescues failing anticancer immune responses, resulting in durable remissions in some cancer patients. Cytokines such as IFNγ and IL-2 contribute to the anti-tumor effect of PD-1 blockade. IL-9...