Pauline Carnell
Overview
Explore the profile of Pauline Carnell including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
7
Citations
28
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Krueger A, Carnell P, Carpenter J
J Pharm Sci
. 2016 Mar;
105(4):1434-43.
PMID: 27019960
In many manufacturing and research areas, the ability to accurately monitor and characterize nanoparticles is becoming increasingly important. Nanoparticle tracking analysis is rapidly becoming a standard method for this characterization,...
2.
Hampton D, Winchester T, Carnell P, Lanfear J
Drug Discov Today
. 2013 Jan;
18(11-12):506-9.
PMID: 23337386
Progress made through technological advances in drug discovery can be undermined by problems with measurement equipment, but it is often difficult to detect the issues without a specific investigation. This...
3.
Blakemore D, Bryans J, Carnell P, Carr C, Chessum N, Field M, et al.
Bioorg Med Chem Lett
. 2009 Dec;
20(2):461-4.
PMID: 20005103
Synthesis of a number of bicyclic five-membered ring derivatives of gabapentin led to the identification of two compounds, (-)-(11A) and (20A) which both had an excellent level of potency against...
4.
Blakemore D, Bryans J, Carnell P, Field M, Kinsella N, Kinsora J, et al.
Bioorg Med Chem Lett
. 2009 Nov;
20(1):248-51.
PMID: 19910190
A range of 3,4-alkylated five-membered ring derivatives of gabapentin were synthesised. One compound (21) had an excellent level of potency against alpha(2)delta and was profiled in in vivo models of...
5.
Blakemore D, Bryans J, Carnell P, Chessum N, Field M, Kinsella N, et al.
Bioorg Med Chem Lett
. 2009 Nov;
20(1):362-5.
PMID: 19897364
A range of 3-alkylated five-membered ring derivatives of Gabapentin were synthesized and several were found to have good levels of potency against the alpha2delta calcium subunit of a voltage-gated calcium...
6.
Mantell S, Gibson K, Osborne S, Maw G, Rees H, Dodd P, et al.
Bioorg Med Chem Lett
. 2009 Mar;
19(8):2190-4.
PMID: 19289283
The SAR of a series of novel pyrido[3,4-d]pyramid-4-ylamine mGluR1 antagonists is described. The multiple of the unbound K(i) in cerebrospinal fluid necessary to give morphine like analgesic effects in an...
7.
Sewing A, Winchester T, Carnell P, Hampton D, Keighley W
Drug Discov Today
. 2008 Mar;
13(5-6):227-33.
PMID: 18342798
Bringing drugs to the market remains a costly and, until now, often unpredictable challenge. Although understanding the underlying science is key to further progress, our imperfect knowledge of disease and...