Paula P Freire
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Explore the profile of Paula P Freire including associated specialties, affiliations and a list of published articles.
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15
Citations
155
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Recent Articles
1.
Fonseca D, Japel M, Gyamfi M, Filgueiras I, Baiochi G, Ostrinski Y, et al.
NPJ Syst Biol Appl
. 2025 Jan;
11(1):7.
PMID: 39805853
Coronavirus disease 2019 (COVID-19) presents a wide spectrum of symptoms, the causes of which remain poorly understood. This study explored the associations between autoantibodies (AABs), particularly those targeting G protein-coupled...
2.
Fonseca D, Filgueiras I, Marques A, Vojdani E, Halpert G, Ostrinski Y, et al.
NPJ Aging
. 2023 Aug;
9(1):21.
PMID: 37620330
Age is a significant risk factor for the coronavirus disease 2019 (COVID-19) severity due to immunosenescence and certain age-dependent medical conditions (e.g., obesity, cardiovascular disorder, and chronic respiratory disease). However,...
3.
Borges L, Guimaraes A, Fonseca D, Freire P, Barreto I, Souza D, et al.
Heliyon
. 2023 Apr;
9(3):e14398.
PMID: 37016723
[This corrects the article DOI: 10.1016/j.heliyon.2022.e11368.].
4.
Baiocchi G, Vojdani A, Rosenberg A, Vojdani E, Halpert G, Ostrinski Y, et al.
J Med Virol
. 2023 Feb;
95(2):e28538.
PMID: 36722456
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is associated with increased levels of autoantibodies targeting immunological proteins such as cytokines and chemokines. Reports further indicate that COVID-19 patients...
5.
Borges L, Guimaraes A, Fonseca D, Freire P, Barreto I, Souza D, et al.
Heliyon
. 2022 Nov;
8(11):e11368.
PMID: 36349284
Brazil experienced one of the most prolonged periods of school closures, and reopening could have exposed students to high rates of SARS-CoV-2 infection. However, the infection status of students and...
6.
Freire P, Cury S, Lopes L, Fernandez G, Liu J, de Moraes L, et al.
Cells
. 2021 Dec;
10(12).
PMID: 34944037
Interleukin-6 (IL-6) is a pro-inflammatory cytokine associated with skeletal muscle wasting in cancer cachexia. The control of gene expression by microRNAs (miRNAs) in muscle wasting involves the regulation of thousands...
7.
Freire P, Marques A, Baiocchi G, Schimke L, Fonseca D, Salgado R, et al.
JCI Insight
. 2021 May;
6(10).
PMID: 34027897
The fact that the COVID-19 fatality rate varies by sex and age is poorly understood. Notably, the outcome of SARS-CoV-2 infections mostly depends on the control of cytokine storm and...
8.
Regulation of myonuclear positioning and muscle function by the skeletal muscle-specific CIP protein
Liu J, Huang Z, Nie M, Wang G, Silva W, Yang Q, et al.
Proc Natl Acad Sci U S A
. 2020 Jul;
117(32):19254-19265.
PMID: 32719146
The appropriate arrangement of myonuclei within skeletal muscle myofibers is of critical importance for normal muscle function, and improper myonuclear localization has been linked to a variety of skeletal muscle...
9.
Vileigas D, Harman V, Freire P, Marciano C, SantAna P, de Souza S, et al.
Sci Rep
. 2019 Dec;
9(1):18050.
PMID: 31792287
Obesity is a pandemic associated with a high incidence of cardiovascular disease; however, the mechanisms are not fully elucidated. Proteomics may provide a more in-depth understanding of the pathophysiological mechanisms...
10.
Scarano W, Bedrat A, Alonso-Costa L, Aquino A, Fantinatti B, Justulin L, et al.
Toxicol Sci
. 2019 Jun;
171(1):84-97.
PMID: 31199487
Environmental exposure to phthalates during intrauterine development might increase susceptibility to neoplasms in reproductive organs such as the prostate. Although studies have suggested an increase in prostatic lesions in adult...