Paula Comune Pennacchi
Overview
Explore the profile of Paula Comune Pennacchi including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
7
Citations
134
Followers
0
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Recent Articles
1.
do Nascimento Pedrosa T, Catarino C, Pennacchi P, Barros S, Maria-Engler S
Methods Mol Biol
. 2021 Jan;
2240:31-41.
PMID: 33423224
This chapter presents the protocols for developing of skin equivalents (SE) and reconstructed human epidermis (RHE) models for dermal toxicity evaluation as an alternative method to animal use in research....
2.
Salles B, da Silva M, Taniguthi L, Ferreira J, Rocha C, Vilegas W, et al.
Biol Pharm Bull
. 2019 Oct;
43(1):169-174.
PMID: 31645529
Different Passiflora species have been appointed as a promising herbal medicine due to antioxidant properties; however, their effect on oxidative process induced by diabetes is still controversial. We aimed to...
3.
Catarino C, do Nascimento Pedrosa T, Pennacchi P, de Assis S, Gimenes F, Consolaro M, et al.
Eur J Pharm Biopharm
. 2018 Jan;
125:51-57.
PMID: 29317274
Currently, there is a strong global trend towards the development of in vitro models to replace the use of animals in safety evaluation tests. Reconstructed Human Epidermis (RHE) models have...
4.
do Nascimento Pedrosa T, Catarino C, Pennacchi P, de Assis S, Gimenes F, Consolaro M, et al.
Toxicol In Vitro
. 2017 Mar;
42:31-37.
PMID: 28344105
Different models of reconstructed human epidermis (RHE) are currently validated to assess skin irritation in vitro and ultimately to the animal replacement of the Draize test. The development of a...
5.
Sandri S, Faiao-Flores F, Tiago M, Pennacchi P, Massaro R, Alves-Fernandes D, et al.
Pharmacol Res
. 2016 Jul;
111:523-533.
PMID: 27436149
The BRAF(V600E) mutation confers constitutive kinase activity and accounts for >90% of BRAF mutations in melanoma. This genetic alteration is a current therapeutic target; however, the antitumorigenic effects of the...
6.
Pennacchi P, Almeida M, Gomes O, Faiao-Flores F, de Araujo Crepaldi M, Dos Santos M, et al.
Tissue Eng Part A
. 2015 Jul;
21(17-18):2417-25.
PMID: 26132636
The advanced glycation end products (AGEs) of proteins are common factors in the pathophysiology of a number of disorders related to aging. The skin generation of AGEs occurs mainly through...
7.
Tiago M, Mendes de Oliveira E, Brohem C, Pennacchi P, Paes R, Haga R, et al.
Tissue Eng Part A
. 2014 Feb;
20(17-18):2412-21.
PMID: 24548268
Melanoma is the most aggressive form of skin cancer and until recently, it was extremely resistant to radio-, immuno-, and chemotherapy. Despite the latest success of BRAF V600E-targeted therapies, responses...