Paula Alvarez Abreu
Overview
Explore the profile of Paula Alvarez Abreu including associated specialties, affiliations and a list of published articles.
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Articles
22
Citations
92
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Recent Articles
1.
Cesar Cirne-Santos C, Gomes Gonzaga D, Oliveira de Resende G, Goncalves M, Andrade A, Furtado Pacheco P, et al.
Curr Top Med Chem
. 2025 Jan;
PMID: 39844553
Background: Zika (ZIKV) is a virus transmitted by mosquitoes that can cause Guillain- Barré syndrome and congenital malformations like microcephaly. Given its explosive resurgence and the resulting epidemics in 2016,...
2.
Francisco Correa de Souza E Souza K, Rabelo V, Abreu P, Santos C, Amaral E Silva N, Luna D, et al.
ACS Omega
. 2024 Sep;
9(34):36835-36846.
PMID: 39220530
Since 1970 acyclovir (ACV) has been the reference drug in treating herpes simplex virus (HSV) infections. However, resistant herpes simplex virus type 1 (HSV-1) strains have emerged, narrowing the treatment...
3.
Borges A, de Andrade Borges A, Ouverney G, Arruda A, Arruda A, Ribeiro A, et al.
Curr Med Chem
. 2024 Jun;
32(2):359-379.
PMID: 38877863
Background: Oral squamous cell carcinoma (OSCC) represents the primary form of oral cancer, posing a significant global health threat. The existing chemotherapy options are accompanied by notable side effects impacting...
4.
Schwenck L, Abreu P, Nunes-da-Fonseca R
Probiotics Antimicrob Proteins
. 2024 Mar;
16(5):1608-1622.
PMID: 38460106
Spiders produce webs, which are still a largely unexplored source of antibacterial compounds, although the reports of its application in the medical field. Therefore, this study aims to present an...
5.
-disubstituted Ureas as Novel Antiplatelet Agents: Synthesis, Pharmacological Evaluation and Studies
de Souza Furtado P, Viana G, de Oliveira A, Rabelo V, Cerqueira I, Paschoal C, et al.
Curr Med Chem
. 2024 Feb;
32(4):806-824.
PMID: 38310396
Introduction: Thrombotic disorders are among the leading causes of morbidity and mortality worldwide. Drugs used in the prevention and treatment of atherothrombosis have pharmacokinetic limitations and adverse effects such as...
6.
Rabelo V, da Silva V, Sanchez Nunez M, Dos Santos Correa Amorim L, Buarque C, Kuhn R, et al.
Future Virol
. 2023 Nov;
18(13):865-880.
PMID: 37974899
Aim: This work aimed to investigate the antiviral activity of two 1,4-disubstituted-1,2,3-triazole derivatives ( and ) against Chikungunya virus (CHIKV) replication. Materials & Methods: Cytotoxicity was analyzed using colorimetric assays...
7.
Machado T, Lima M, da Silva R, Macedo A, de Queiroz L, Angrisani B, et al.
Biomedicines
. 2023 Jul;
11(7).
PMID: 37509552
Oral squamous cell carcinoma (OSCC) is a worldwide public health problem, with high morbidity and mortality rates. The development of new drugs to treat OSCC is paramount. plant species have...
8.
Souza M, de Melo C, Faro L, Fragel-Madeira L, Giongo V, Abreu P, et al.
Curr Top Med Chem
. 2022 Dec;
23(4):257-264.
PMID: 36545716
Background: Since the emergence of HSV resistant strains, new antiviral agents have emerged and still are urgently needed, especially those with alternative targets. Objective: In this work, we evaluated new...
9.
Rabelo V, Nunes de Palmer Paixao I, Abreu P
J Mol Model
. 2022 Sep;
28(10):311.
PMID: 36097090
Chikungunya virus (CHIKV) is the etiological agent of the Chikungunya fever which has spread worldwide. Clinically, this disease may lead to prolonged incapacitating joint pain that can compromise remarkably the...
10.
Costa Zorzanelli B, Ouverney G, Pauli F, da Fonseca A, de Almeida E, de Carvalho D, et al.
Molecules
. 2022 Aug;
27(16).
PMID: 36014389
Oral squamous cell carcinoma (OSCC) is a global public health problem with high incidence and mortality. The chemotherapeutic agents used in the clinic, alone or in combination, usually lead to...