Paul T Winnard Jr
Overview
Explore the profile of Paul T Winnard Jr including associated specialties, affiliations and a list of published articles.
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Articles
37
Citations
1125
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0
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Recent Articles
1.
Winnard Jr P, Vesuna F, Raman V
Antiviral Res
. 2025 Jan;
235:106098.
PMID: 39889906
Viruses have co-evolved with their hosts, intertwining their life cycles. As a result, components and pathways from a host cell's processes are appropriated for virus infection. This review examines the...
2.
Winnard Jr P, Vesuna F, Bol G, Gabrielson K, Chenevix-Trench G, Ter Hoeve N, et al.
Cancer Lett
. 2024 Sep;
604:217260.
PMID: 39306228
Patients who present with breast cancer bone metastasis only have limited palliative treatment strategies and efficacious drug treatments are needed. In breast cancer patient data, high levels of the RNA...
3.
Isogenic Cell Lines Derived from Specific Organ Metastases Exhibit Divergent Cytogenomic Aberrations
Winnard Jr P, Morsberger L, Yonescu R, Jiang L, Zou Y, Raman V
Cancers (Basel)
. 2023 Mar;
15(5).
PMID: 36900209
Aneuploidy, a deviation in chromosome numbers from the normal diploid set, is now recognized as a fundamental characteristic of all cancer types and is found in 70-90% of all solid...
4.
Roux A, Winnard Jr P, Van Voss M, Muller L, Jackson S, Hoffer B, et al.
Mol Cell Biochem
. 2023 Mar;
478(11):2567-2580.
PMID: 36884151
Breast cancer brain metastasis (BCBM) has an incidence of 10-30%. It is incurable and the biological mechanisms that promote its progression remain largely undefined. Consequently, to gain insights into BCBM...
5.
Vesuna F, Akhrymuk I, Smith A, Winnard Jr P, Lin S, Panny L, et al.
Front Microbiol
. 2022 Sep;
13:959577.
PMID: 36090095
SARS-CoV-2, the virus behind the deadly COVID-19 pandemic, continues to spread globally even as vaccine strategies are proving effective in preventing hospitalizations and deaths. However, evolving variants of the virus...
6.
Winnard Jr P, Vesuna F, Raman V
Antiviral Res
. 2020 Dec;
185:104994.
PMID: 33301755
DDX3X or DDX3, a member of the DEAD (asp, glu, ala, asp) box RNA helicase family of proteins, is a multifunctional protein, which is usurped by several viruses and is...
7.
Winnard Jr P, Vesuna F, Muthukumar S, Raman V
PLoS One
. 2020 Nov;
15(11):e0242384.
PMID: 33196681
Background: Monitoring and treating metastatic progression remains a formidable task due, in part, to an inability to monitor specific differential molecular adaptations that allow the cancer to thrive within different...
8.
Winnard Jr P, Bharti S, Sharma R, Krishnamachary B, Mironchik Y, Penet M, et al.
J Cachexia Sarcopenia Muscle
. 2020 Oct;
11(6):1487-1500.
PMID: 33006443
Background: Cachexia is a major cause of morbidity in pancreatic ductal adenocarcinoma (PDAC) patients. Our purpose was to understand the impact of PDAC-induced cachexia on brain metabolism in PDAC xenograft...
9.
Tantravedi S, Vesuna F, Winnard Jr P, Martin A, Lim M, Eberhart C, et al.
Transl Oncol
. 2018 Oct;
12(1):96-105.
PMID: 30292066
Medulloblastoma is the most common malignant tumor that arises from the cerebellum of the central nervous system. Clinically, medulloblastomas are treated by surgery, radiation, and chemotherapy, all of which result...
10.
Zhang C, Winnard Jr P, Dasari S, Kominsky S, Doucet M, Jayaraman S, et al.
Chem Sci
. 2018 Apr;
9(3):743-753.
PMID: 29629144
Breast neoplasms frequently colonize bone and induce development of osteolytic bone lesions by disrupting the homeostasis of the bone microenvironment. This degenerative process can lead to bone pain and pathological...