Paul Spellman
Overview
Explore the profile of Paul Spellman including associated specialties, affiliations and a list of published articles.
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49
Citations
4408
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Recent Articles
1.
Vermehren-Schmaedick A, Peto M, Wagoner W, Chiotti K, Ramsey E, Wang X, et al.
PLoS One
. 2024 May;
19(5):e0302856.
PMID: 38722955
Metastasis is the most dreaded outcome after a breast cancer diagnosis, and little is known regarding what triggers or promotes breast cancer to spread distally, or how to prevent or...
2.
Lindner J, Davidson B, Song Z, Maier C, Minnier J, Stevens J, et al.
Metabolites
. 2021 Oct;
11(10).
PMID: 34677363
Coronary microvascular dysfunction (MVD) is a syndrome of abnormal regulation of vascular tone, particularly during increased metabolic demand. While there are several risk factors for MVD, some of which are...
3.
Minnier J, Rajeevan N, Gao L, Park B, Pyarajan S, Spellman P, et al.
JCO Precis Oncol
. 2021 Aug;
5.
PMID: 34381935
Materials And Methods: Clinical BC risk prediction models were validated in combination with a genetic polygenic risk score of 313 (PRS313) single-nucleotide polymorphisms in genetic females without prior BC diagnosis...
4.
Matsumoto T, Wakefield L, Peters A, Peto M, Spellman P, Grompe M
Nat Commun
. 2021 Jan;
12(1):646.
PMID: 33510149
Polyploidy is a hallmark of cancer, and closely related to chromosomal instability involved in cancer progression. Importantly, polyploid cells also exist in some normal tissues. Polyploid hepatocytes proliferate and dynamically...
5.
Amara S, Kuiken H, Selfors L, Butler T, Leung M, Leung C, et al.
Nat Commun
. 2020 Nov;
11(1):5799.
PMID: 33199705
The extent and importance of functional heterogeneity and crosstalk between tumor cells is poorly understood. Here, we describe the generation of clonal populations from a patient-derived ovarian clear cell carcinoma...
6.
Berlow N, Grasso C, Quist M, Cheng M, Gandour-Edwards R, Hernandez B, et al.
Sarcoma
. 2020 Jun;
2020:6312480.
PMID: 32565715
Nonrhabdomyosarcoma soft-tissue sarcomas (STSs) are a class of 50+ cancers arising in muscle and soft tissues of children, adolescents, and adults. Rarity of each subtype often precludes subtype-specific preclinical research,...
7.
Heskett M, Smith L, Spellman P, Thayer M
RNA
. 2020 Mar;
26(6):724-738.
PMID: 32144193
DNA replication occurs on mammalian chromosomes in a cell-type distinctive temporal order known as the replication timing program. We previously found that disruption of the noncanonical lncRNA genes and results...
8.
Rozanov D, Cheltsov A, Nilsen A, Boniface C, Forquer I, Korkola J, et al.
PLoS One
. 2019 Mar;
14(3):e0205623.
PMID: 30908483
To determine the target of the recently identified lead compound NSC130362 that is responsible for its selective anti-cancer efficacy and safety in normal cells, structure-activity relationship (SAR) studies were conducted....
9.
Cornforth M, Anur P, Wang N, Robinson E, Ray F, Bedford J, et al.
Radiat Res
. 2018 May;
190(1):88-97.
PMID: 29749794
Chromosome rearrangements are large-scale structural variants that are recognized drivers of oncogenic events in cancers of all types. Cytogenetics allows for their rapid, genome-wide detection, but does not provide gene-level...
10.
Okunieff P, Casey-Sawicki K, Lockney N, Hoppe B, Enderling H, Pinnix C, et al.
Clin Cancer Res
. 2018 Apr;
24(15):3500-3509.
PMID: 29661779
The Radiation Therapy Committee of SWOG periodically evaluates its strategic plan in an effort to maintain a current and relevant scientific focus, and to provide a standard platform for future...