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Paul Spagnuolo

Explore the profile of Paul Spagnuolo including associated specialties, affiliations and a list of published articles. Areas
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Articles 5
Citations 338
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Recent Articles
1.
Ford N, Spagnuolo P, Kraft J, Bauer E
Foods . 2023 Jul; 12(13). PMID: 37444254
Avocados () are a unique fruit that can provide health benefits when included in a healthy diet. As health care moves towards precision health and targeted therapies or preventative medicine,...
2.
Chandran A, Jayasankar V, Spagnuolo P, Subramanian J
Crit Rev Oncog . 2023 May; 27(3):23-31. PMID: 37183936
Acute myeloid leukemia (AML) is an aggressive blood cancer with limited chemotherapy options and negative patient outcomes. Investigations with bioactive compounds from dietary sources against cancer have increased in the...
3.
Spagnuolo P
J Pharm Pharm Sci . 2015 Dec; 18(4):339-43. PMID: 26626240
Purpose: Concomitant use of nutraceuticals with chemotherapy is very common. Cancer patients self-medicate to relieve the side effects associated with chemotherapy, improve disease outcome and to regain control of their...
4.
Drewry J, Duodu E, Mazouchi A, Spagnuolo P, Burger S, Gradinaru C, et al.
Inorg Chem . 2012 Jul; 51(15):8284-91. PMID: 22784241
Src Homology 2 (SH2) domains are the paradigm of phosphotyrosine (pY) protein recognition modules and mediate numerous cancer-promoting protein-protein complexes. Effective SH2 domain mimicry with pY-binding coordination complexes offers a...
5.
Skrtic M, Sriskanthadevan S, Jhas B, Gebbia M, Wang X, Wang Z, et al.
Cancer Cell . 2011 Nov; 20(5):674-88. PMID: 22094260
To identify FDA-approved agents targeting leukemic cells, we performed a chemical screen on two human leukemic cell lines and identified the antimicrobial tigecycline. A genome-wide screen in yeast identified mitochondrial...