Paul Sopp
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Explore the profile of Paul Sopp including associated specialties, affiliations and a list of published articles.
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21
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1410
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Recent Articles
1.
Randall E, Sopp P, Raper A, Dry I, Burdon T, Hope J, et al.
Sci Rep
. 2024 Jul;
14(1):14974.
PMID: 38951667
Bovine alveolar macrophages (AMs) defend the lungs against pathogens such as Mycobacterium bovis (M. bovis), the causative agent of bovine tuberculosis. However, little is known about the surface molecules expressed...
2.
Hamid M, Cespedes P, Jin C, Chen J, Gileadi U, Antoun E, et al.
Nat Immunol
. 2024 Apr;
25(5):834-846.
PMID: 38561495
Cancer remains one of the leading causes of mortality worldwide, leading to increased interest in utilizing immunotherapy strategies for better cancer treatments. In the past decade, CD103 T cells have...
3.
Turkalj S, Jakobsen N, Groom A, Metzner M, Riva S, Gur E, et al.
Cell Stem Cell
. 2023 May;
30(5):722-740.e11.
PMID: 37146586
Understanding clonal evolution and cancer development requires experimental approaches for characterizing the consequences of somatic mutations on gene regulation. However, no methods currently exist that efficiently link high-content chromatin accessibility...
4.
Yin Z, Chen J, Lu Y, Wang B, Godfrey L, Mentzer A, et al.
Cell Rep
. 2023 May;
42(5):112470.
PMID: 37141092
Most existing studies characterizing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-specific T cell responses are peptide based. This does not allow evaluation of whether tested peptides are processed and presented...
5.
Peng Y, Felce S, Dong D, Penkava F, Mentzer A, Yao X, et al.
Nat Immunol
. 2021 Dec;
23(1):50-61.
PMID: 34853448
NP-B*07:02-specific CD8 T cell responses are considered among the most dominant in SARS-CoV-2-infected individuals. We found strong association of this response with mild disease. Analysis of NP-B*07:02-specific T cell clones...
6.
Peng Y, Mentzer A, Liu G, Yao X, Yin Z, Dong D, et al.
Nat Immunol
. 2020 Sep;
21(11):1336-1345.
PMID: 32887977
The development of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines and therapeutics will depend on understanding viral immunity. We studied T cell memory in 42 patients following recovery from...
7.
Peng Y, Mentzer A, Liu G, Yao X, Yin Z, Dong D, et al.
bioRxiv
. 2020 Jun;
PMID: 32577665
COVID-19 is an ongoing global crisis in which the development of effective vaccines and therapeutics will depend critically on understanding the natural immunity to the virus, including the role of...
8.
Li X, Wang R, Fan P, Yao X, Qin L, Peng Y, et al.
Front Oncol
. 2019 Nov;
9:1066.
PMID: 31709176
Cancer patients often display dysfunctional antitumor T-cell responses. Because noteworthy benefits of immune checkpoint pathway blockade, such as programmed cell death protein 1 (PD-1) inhibitors, have been achieved in multiple...
9.
Chagraoui H, Kristiansen M, Ruiz J, Serra-Barros A, Richter J, Hall-Ponsele E, et al.
Nat Commun
. 2018 Dec;
9(1):5375.
PMID: 30560907
During development, it is unclear if lineage-fated cells derive from multilineage-primed progenitors and whether active mechanisms operate to restrict cell fate. Here we investigate how mesoderm specifies into blood-fated cells....
10.
Mettananda S, Fisher C, Hay D, Badat M, Quek L, Clark K, et al.
Nat Commun
. 2017 Sep;
8(1):424.
PMID: 28871148
β-Thalassemia is one of the most common inherited anemias, with no effective cure for most patients. The pathophysiology reflects an imbalance between α- and β-globin chains with an excess of...