Paul Sopp
Overview
Explore the profile of Paul Sopp including associated specialties, affiliations and a list of published articles.
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21
Citations
1410
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Recent Articles
11.
Giustacchini A, Thongjuea S, Barkas N, Woll P, Povinelli B, Booth C, et al.
Nat Med
. 2017 May;
23(6):692-702.
PMID: 28504724
Recent advances in single-cell transcriptomics are ideally placed to unravel intratumoral heterogeneity and selective resistance of cancer stem cell (SC) subpopulations to molecularly targeted cancer therapies. However, current single-cell RNA-sequencing...
12.
Werling D, Hope J, Siddiqui N, Widdison S, Russell C, Sopp P, et al.
Front Vet Sci
. 2017 Apr;
4:44.
PMID: 28421187
Within the ruminant system, several possibilities exist to generate dendritic cells migrating out from the tissue into the regional draining lymph nodes as afferent lymph dendritic cells (ALDCs). Here, we...
13.
Handel A, Chintawar S, Lalic T, Whiteley E, Vowles J, Giustacchini A, et al.
Hum Mol Genet
. 2016 Jan;
25(5):989-1000.
PMID: 26740550
Induced pluripotent stem cell (iPSC)-derived cortical neurons potentially present a powerful new model to understand corticogenesis and neurological disease. Previous work has established that differentiation protocols can produce cortical neurons,...
14.
Graham E, Thom M, Howard C, Boysen P, Storset A, Sopp P, et al.
Vet Immunol Immunopathol
. 2009 Jun;
132(2-4):101-8.
PMID: 19525013
Natural killer (NK) cells are critical to the innate defence against intracellular infection. High NK cell frequencies have been detected in human neonates, which may compensate for the relative immaturity...
15.
Clark J, Billington K, Bumstead J, Oakes R, Soon P, Sopp P, et al.
Mol Biochem Parasitol
. 2008 Aug;
162(1):77-86.
PMID: 18723051
Stable transfection of Eimeria species has been difficult to achieve because of the obligate requirement for in vivo amplification and selection of the parasites. Strategies to generate and stabilise populations...
16.
Sopp P, Werling D, Baldwin C
Vet Immunol Immunopathol
. 2007 Aug;
119(1-2):106-14.
PMID: 17675249
A panel of 377 commercially available mAbs were submitted to the animal homologue section of the 8th International Workshop on Human Leukocyte Differentiation Antigens (HLDA8, Adelaide, Australia) for cross-reactivity studies...
17.
Price S, Sopp P, Howard C, Hope J
Immunology
. 2006 Oct;
120(1):57-65.
PMID: 17034425
Gammadelta T-cell receptor(+) T lymphocytes are an important element of the innate immune system. Early production of interferon (IFN)-gamma by gammadelta T cells may have a role in linking innate...
18.
Saalmuller A, Lunney J, Daubenberger C, Davis W, Fischer U, Gobel T, et al.
Cell Immunol
. 2005 Oct;
236(1-2):51-8.
PMID: 16198325
Development of reagents against leukocyte differentiation antigens in veterinary immunology is slower compared to humans and mice. Cross-reactivity studies with monoclonal antibodies (mAb) generated against human molecules represent an excellent...
19.
Menge C, Stamm I, van Diemen P, Sopp P, Baljer G, Wallis T, et al.
J Med Microbiol
. 2004 May;
53(Pt 6):573-579.
PMID: 15150340
Ruminants are a major reservoir of enterohaemorrhagic Escherichia coli (EHEC), which cause acute gastroenteritis in humans with potentially life-threatening sequelae. The mechanisms underlying EHEC persistence in ruminant hosts are poorly...
20.
Guergnon J, Chaussepied M, Sopp P, Lizundia R, Moreau M, Blumen B, et al.
Cell Microbiol
. 2003 Sep;
5(10):709-16.
PMID: 12969376
Theileria infection of bovine leucocytes induces uncontrolled proliferation and a transformed phenotype comparable to tumour cells. Infected cells have many characteristics of activated leucocytes and use autocrine loops to augment...