Paul Schilf
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Explore the profile of Paul Schilf including associated specialties, affiliations and a list of published articles.
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21
Citations
181
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Recent Articles
1.
Olbrich M, Hartmann A, Kunzel S, Aherrahrou Z, Schilf P, Baines J, et al.
Pharmacol Res
. 2024 May;
205:107231.
PMID: 38815878
We previously demonstrated that mice carrying natural mtDNA variants of the FVB/NJ strain (m.7778 G>T in the mt-Atp8 gene in mitochondrial complex V), namely C57BL/6 J-mt (B6-mtFVB), exhibited (i) partial...
2.
Akbarzadeh R, Czyz C, Thomsen S, Schilf P, Murthy S, Sadik C, et al.
Front Immunol
. 2023 Dec;
14:1241461.
PMID: 38116004
Monocytes play a significant role in the pathogenesis of most inflammatory diseases, including autoimmune diseases. Herein, different subpopulations of monocytes often play differential, partially antagonistic roles, in the regulation of...
3.
Guerrero-Juarez C, Schilf P, Li J, Zappia M, Bao L, Patel P, et al.
Front Immunol
. 2023 Oct;
14:1266359.
PMID: 37799716
Introduction: Inflammatory epidermolysis bullosa acquisita (EBA) is characterized by a neutrophilic response to anti-type VII collagen (COL7) antibodies resulting in the development of skin inflammation and blistering. The antibody transfer...
4.
Kunstner A, Schilf P, Busch H, Ibrahim S, Hirose M
Int J Mol Sci
. 2022 Feb;
23(3).
PMID: 35162979
We recently reported on two mouse strains carrying different single nucleotide variations in the mitochondrial complex I gene, i.e., B6-mt mice carrying m.11902T>C and B6-mt carrying m.4738C>A. B6-mt mice exhibited...
5.
Zaher D, Ramadan W, El-Awady R, Omar H, Hersi F, Srinivasulu V, et al.
Cancers (Basel)
. 2021 Jul;
13(11).
PMID: 34200264
(1) Background: Today, the discovery of novel anticancer agents with multitarget effects and high safety margins represents a high challenge. Drug discovery efforts indicated that benzopyrane scaffolds possess a wide...
6.
Murthy S, Schilf P, Patzelt S, Thieme M, Becker M, Kroger L, et al.
J Invest Dermatol
. 2021 May;
141(11):2587-2595.e2.
PMID: 34033839
Epidermolysis bullosa acquisita and mucous membrane pemphigoid are autoimmune blistering diseases characterized by mucocutaneous blisters elicited by an autoantibody-mediated immune response against specific proteins of the epidermal basement membrane. The...
7.
Schilf P, Schmitz M, Derenda-Hell A, Thieme M, Bremer T, Vaeth M, et al.
J Invest Dermatol
. 2021 Feb;
141(7):1646-1655.e3.
PMID: 33609554
Bullous pemphigoid-like epidermolysis bullosa acquisita (EBA) is an autoantibody-driven, granulocyte-mediated skin disease. The role of cellular metabolism and its potential as a therapeutic target in EBA are unknown. We investigated...
8.
Schilf P, Kunstner A, Olbrich M, Waschina S, Fuchs B, Galuska C, et al.
Int J Mol Sci
. 2021 Jan;
22(3).
PMID: 33498298
Several genetic variants in the mitochondrial genome (mtDNA), including ancient polymorphisms, are associated with chronic inflammatory conditions, but investigating the functional consequences of such mtDNA polymorphisms in humans is challenging...
9.
Srinivasulu V, Schilf P, Ibrahim S, Shehadi I, Malik O, Sieburth S, et al.
J Org Chem
. 2020 Aug;
85(16):10695-10708.
PMID: 32806094
Nitrogen and oxygen medium rings, in particular nine-membered rings, epitomize a unique area of chemical space that occurs in many natural products and biologically appealing compounds. The scarcity of 8-...
10.
Vorobyev A, Gupta Y, Sezin T, Koga H, Bartsch Y, Belheouane M, et al.
Nat Commun
. 2019 Sep;
10(1):4097.
PMID: 31506438
Phenotypic variation of quantitative traits is orchestrated by a complex interplay between the environment (e.g. diet) and genetics. However, the impact of gene-environment interactions on phenotypic traits mostly remains elusive....