Paul Ruff
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Explore the profile of Paul Ruff including associated specialties, affiliations and a list of published articles.
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Articles
87
Citations
5013
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Recent Articles
1.
Dubner J, Neugut A, Joffe M, ONeil D, Ayeni O, Chen W, et al.
Lancet Glob Health
. 2024 Nov;
12(12):e1993-e2002.
PMID: 39577973
Background: Breast cancer is the most common malignancy diagnosed among women in South Africa, with the aggressive triple-negative subtype comprising approximately 15% of breast cancers in this population. South Africa...
2.
Cohen G, Rapoport B, Chan S, Ruff P, Arance A, Mujika Eizmendi K, et al.
PLoS One
. 2024 Nov;
19(11):e0309778.
PMID: 39531423
Intravenous pembrolizumab 400 mg every 6 weeks was approved across tumor types based on pharmacokinetic modeling, which showed exposures consistent with previous standard dosing of 200 mg or 2 mg/kg...
3.
Ubanako P, Mirza S, Ruff P, Penny C
Front Mol Biosci
. 2024 Oct;
11:1447953.
PMID: 39355533
The discovery of novel and innovative therapeutic strategies for cancer treatment and management remains a major global challenge. Exosomes are endogenous nanoscale extracellular vesicles that have garnered increasing attention as...
4.
5.
Dull P, Achilles S, Ahmed R, Barnabas R, Campos N, Chirgwin K, et al.
Vaccine
. 2024 Jul;
42(25):126100.
PMID: 39004526
Cervical cancer is a major cause of morbidity and mortality globally with a disproportionate impact on women in low- and middle-income countries. In 2021, the World Health Organization (WHO) called...
6.
ONeil D, Blanchard C, Joffe M, Antoni M, Ream M, Mmoledi K, et al.
Res Sq
. 2024 Jul;
PMID: 38978566
Purpose: We aimed to evaluate for associations between HIV status, psychosocial factors, and adjuvant endocrine therapy (AET) adherence in South African (SA) women with estrogen receptor positive (ER+) breast cancer...
7.
Carbonell C, Adegbulugbe A, Cheung W, Ruff P
JCO Glob Oncol
. 2024 Jun;
10:e2300455.
PMID: 38935883
Quality improvement (QI) programs have rapidly grown in health care over recent years. Despite increasing evidence of successful QI initiatives resulting in improved outcomes, the adoption and implementation of QI...
8.
Mapanga W, Ayeni O, Chen W, Jacobson J, Neugut A, Ruff P, et al.
PLOS Glob Public Health
. 2023 Oct;
3(10):e0002432.
PMID: 37874786
The South African Breast Cancer and HIV Outcomes prospective cohort (SABCHO) study was established to investigate survival determinants among HIV-positive and HIV-negative SA women with breast cancer. This paper describes...
9.
Dix-Peek T, Dickens C, Augustine T, Phakathi B, Van Den Berg E, Joffe M, et al.
Mol Med Rep
. 2023 Oct;
28(6).
PMID: 37830168
Black African populations are more genetically diverse than others, but genetic variants have been studied primarily in European populations. The present study examined the association of four single nucleotide polymorphisms...
10.
Joffe M, Ayeni O, Mapanga W, Ruff P, Murugan N, Cubasch H, et al.
Glob Health Action
. 2023 Jul;
16(1):2228567.
PMID: 37431748
There is a rising noncommunicable disease (NCD) burden in low- and middle-income countries. Sub-Saharan Africa (SSA) bears a higher burden than the global average with South Africa (SA) enduring the...