Paul R Van Ginkel
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Explore the profile of Paul R Van Ginkel including associated specialties, affiliations and a list of published articles.
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Articles
17
Citations
356
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Recent Articles
1.
Flynn C, Ginkel P, Hubert K, Guo Q, Hrycaj S, McDermott A, et al.
Development
. 2023 Feb;
150(4).
PMID: 36815629
Interstitial stromal cells play critical roles in muscle development, regeneration and repair and we have previously reported that Hoxa11 and Hoxd11 are expressed in the interstitial cells of muscles attached...
2.
Scariot P, Papoti M, Polisel E, Bordon Orsi J, Ginkel P, Prolla T, et al.
Life Sci
. 2023 Jan;
317:121443.
PMID: 36709910
There is a scarcity of data regarding the acclimation to high altitude (hypoxic environment) accompanied by training at low altitude (normoxic conditions), the so-called "living high-training low" (LHTL) model in...
3.
Dhillon R, Qin Y, Ginkel P, Fu V, Vann J, Lawton A, et al.
Aging Cell
. 2022 Oct;
21(12):e13721.
PMID: 36199173
Mitochondrial NAD -dependent protein deacetylase Sirtuin3 (SIRT3) has been proposed to mediate calorie restriction (CR)-dependent metabolic regulation and lifespan extension. Here, we investigated the role of SIRT3 in CR-mediated longevity,...
4.
Li M, Marty-Santos L, Ginkel P, McDermott A, Rasky A, Lukacs N, et al.
Front Cell Dev Biol
. 2021 Dec;
9:767454.
PMID: 34901011
genes encode transcription factors that are critical for embryonic skeletal patterning and organogenesis. The , , and paralogs are expressed in the lung mesenchyme and function redundantly during embryonic lung...
5.
Scariot P, Manchado-Gobatto F, Ginkel P, Prolla T, Gobatto C
Brain Res Bull
. 2021 Jul;
175:116-129.
PMID: 34303768
Background: Oxidation resistance protein 1 (OXR1) is of scientific interest due its role in protecting tissues against oxidative stress, DNA mutations and tumorigenesis, but little is known regarding strategies to...
6.
Clark P, Bhattacharya S, Elmayan A, Darjatmoko S, Thuro B, Yan M, et al.
J Neurosurg
. 2016 Jul;
126(5):1448-1460.
PMID: 27419830
OBJECTIVE Glioblastoma multiforme (GBM) is an aggressive brain cancer with median survival of less than 2 years with current treatment. Glioblastomas exhibit extensive intratumoral and interpatient heterogeneity, suggesting that successful...
7.
Ginkel P, Yan M, Bhattacharya S, Polans A, Kenealey J
Toxicol Appl Pharmacol
. 2015 Sep;
288(3):453-62.
PMID: 26341291
Paclitaxel, etoposide, vincristine and doxorubicin are examples of natural products being used as chemotherapeutics but with adverse side effects that limit their therapeutic window. Natural products derived from plants and...
8.
Rezaie Kanavi M, Darjatmoko S, Wang S, Azari A, Farnoodian M, Kenealey J, et al.
Molecules
. 2014 Nov;
19(11):17578-603.
PMID: 25361423
The objective of this study was to determine whether resveratrol or a defined, reconstituted grape powder can attenuate the formation of new blood vessels in a mouse model of choroidal...
9.
Kenealey J, Subramanian L, Ginkel P, Darjatmoko S, Lindstrom M, Somoza V, et al.
J Agric Food Chem
. 2011 Mar;
59(9):4979-86.
PMID: 21401048
Resveratrol, a nontoxic polyphenol, has been shown to inhibit tumor growth in a xenograft mouse model of neuroblasoma. However, resveratrol is rapidly metabolized, mainly to its glucuronidated and sulfated derivatives....
10.
Subramanian L, Youssef S, Bhattacharya S, Kenealey J, Polans A, Ginkel P
Clin Cancer Res
. 2010 Nov;
16(24):5942-8.
PMID: 21045084
Low cancer survival rates and the serious side effects often associated with current chemotherapeutics highlight the need for new and effective nontoxic anticancer agents. Since 1997 when Jang and colleagues...