Paul R Lephart
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Explore the profile of Paul R Lephart including associated specialties, affiliations and a list of published articles.
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42
Citations
783
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Recent Articles
1.
Wangchinda W, Aitken S, Klatt M, Lephart P, Smith A, Pogue J
Open Forum Infect Dis
. 2024 Nov;
11(11):ofae643.
PMID: 39582504
Background: Guidelines suggest dual antipseudomonal therapy for empiric treatment of pneumonia caused by gram-negative bacteria in intensive care unit (ICU) patients. Additionally, consideration of local susceptibility data and patient-specific risk...
2.
Miller K, Toiv A, Deng C, Lu M, Niziol L, Hart J, et al.
Curr Eye Res
. 2024 Jan;
49(4):339-344.
PMID: 38179803
Purpose: Negative laboratory results make targeting microbial keratitis treatment difficult. We investigated factors associated with laboratory negativity in patients with microbial keratitis in the context of a transition to a...
3.
Hart J, Lu M, Tracey B, Miller K, Lephart P, Mian S, et al.
Curr Eye Res
. 2023 Oct;
49(1):39-45.
PMID: 37815382
Purpose: Evaluate the effect of corneal and contact lens-related (CLR) culture results on visual acuity (VA) in patients with microbial keratitis (MK). Methods: MK patients with corneal and CLR cultures...
4.
Kang L, Lu M, Niziol L, Greenwald M, Mian S, Thibodeau A, et al.
Cornea
. 2023 Jan;
42(12):1488-1496.
PMID: 36716402
Purpose: The aim of the study was to describe the pathogen, antimicrobial susceptibility, and trends over time of microbial keratitis (MK) at a Midwestern tertiary eye center. Methods: Patients with...
5.
Schroeder L, Bachman M, Idoni A, Gegenheimer-Holmes J, Kronick S, Valdez R, et al.
J Appl Lab Med
. 2021 Nov;
7(3):661-673.
PMID: 34755849
Background: Diagnostic sensitivities of point-of-care SARS-CoV-2 assays depend on specimen type and population-specific viral loads. Evaluation of these assays require "direct" specimens from paired-swab studies rather than more accessible residual...
6.
Lephart P, Bachman M, LeBar W, McClellan S, Barron K, Schroeder L, et al.
Diagn Microbiol Infect Dis
. 2020 Sep;
99(1):115200.
PMID: 32980807
The COVID-19 pandemic in the United States created a unique situation where multiple molecular SARS-CoV-2 diagnostic assays rapidly received Emergency Use Authorization by the FDA and were validated by laboratories...
7.
Brouwer A, Myers J, Martin E, Konopka K, Lauring A, Eisenberg M, et al.
Clin Infect Dis
. 2020 Sep;
72(10):e580-e585.
PMID: 32877923
Background: Given the challenges in implementing widespread testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), there is increasing interest in alternative surveillance strategies. Methods: We tested nasopharyngeal swabs from...
8.
Claeys K, Heil E, Pogue J, Lephart P, Johnson J
Diagn Microbiol Infect Dis
. 2018 Feb;
91(2):144-146.
PMID: 29449043
Verigene Blood-Culture Gram-Negative (GN) results in rapid identification of key GNs in bloodstream infections. Its use clinically is limited by low sensitivity in polymicrobial GN infections and concerns for inappropriate...
9.
Zaidenstein R, Miller A, Tal-Jasper R, Ofer-Friedman H, Sklarz M, Katz D, et al.
Microorganisms
. 2018 Jan;
6(1).
PMID: 29337862
It is unknown as to whether other beta-lactams can be used for bloodstream infections (BSI) resulting from (PA) which are non-susceptible to one or more carbapenem. We conducted a retrospective...
10.
Dhar S, Martin E, Lephart P, McRoberts J, Chopra T, Burger T, et al.
Open Forum Infect Dis
. 2016 Feb;
3(1):ofv213.
PMID: 26885543
A "high risk" clone of carbapenem-resistant Klebsiella pneumoniae (CRKP) identified by multilocus sequence typing (MLST) as sequence type (ST) 258 has disseminated worldwide. As the molecular epidemiology of the CRE...