Paul Primakoff
Overview
Explore the profile of Paul Primakoff including associated specialties, affiliations and a list of published articles.
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Articles
17
Citations
533
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Recent Articles
1.
Nishimura H, Gupta S, Myles D, Primakoff P
Reproduction
. 2011 Jan;
141(4):437-51.
PMID: 21273369
TMEM190, a small transmembrane protein containing the trefoil domain, was previously identified by our proteomic analysis of mouse sperm. Two structural features of TMEM190, 'trefoil domain' and 'small transmembrane protein',...
2.
Zhu G, Gupta S, Myles D, Primakoff P
Mol Reprod Dev
. 2009 Aug;
76(11):1106-14.
PMID: 19670298
ADAM family members play important roles in various physiological and pathological processes, for example, fertilization, embryogenesis, neurogenesis, and development of asthma and arthritis (Primakoff and Myles, 2000. Trends Genet 16:...
3.
Ellerman D, Pei J, Gupta S, Snell W, Myles D, Primakoff P
Mol Reprod Dev
. 2009 Aug;
76(12):1188-99.
PMID: 19658160
Izumo, a sperm membrane protein, is essential for gamete fusion in the mouse. It has an Immunoglobulin (Ig) domain and an N-terminal domain for which neither the functions nor homologous...
4.
Gupta S, Primakoff P, Myles D
Mol Reprod Dev
. 2009 Apr;
76(7):602.
PMID: 19363789
No abstract available.
5.
He Z, Gupta S, Myles D, Primakoff P
Mol Reprod Dev
. 2008 Dec;
76(7):629-36.
PMID: 19107828
CD9, a member of the tetraspanin family, associates with a variety of other proteins to form the tetraspanin web. CD9 forms direct and relatively stable associations with the immunoglobulin superfamily...
6.
Nishimura H, Myles D, Primakoff P
J Biol Chem
. 2007 Apr;
282(24):17900-7.
PMID: 17439939
Male mice lacking ADAM2 (fertilin beta) or ADAM3 (cyritestin) are infertile; cauda epididymal sperm (mature sperm) from these mutant mice cannot bind to the egg zona pellucida. ADAM3 is barely...
7.
Primakoff P, Myles D
FEBS Lett
. 2007 Mar;
581(11):2174-80.
PMID: 17328899
The mechanism of sperm-egg fusion in mammals is a research area that has greatly benefited from the use of gene deletion technology. Because fertilization is internal in mammals and the...
8.
Runge K, Evans J, He Z, Gupta S, McDonald K, Stahlberg H, et al.
Dev Biol
. 2007 Jan;
304(1):317-25.
PMID: 17239847
Microvilli are found on the surface of many cell types, including the mammalian oocyte, where they are thought to act in initial contact of sperm and oocyte plasma membranes. CD9...
9.
Stein K, Go J, Lane W, Primakoff P, Myles D
Proteomics
. 2006 Jun;
6(12):3533-43.
PMID: 16758446
The sperm interacts with three oocyte-associated structures during fertilization: the cumulus cell layer surrounding the oocyte, the egg extracellular matrix (the zona pellucida), and the oocyte plasma membrane. Each of...
10.
Ellerman D, Myles D, Primakoff P
Dev Cell
. 2006 Jun;
10(6):831-7.
PMID: 16740484
In mammals, sperm-egg interaction is based on molecular events either unique to gametes or also present in somatic cells. In gamete fusion, it is unknown which features are gamete specific...