Paul Peluso
Overview
Explore the profile of Paul Peluso including associated specialties, affiliations and a list of published articles.
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Articles
29
Citations
7686
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Recent Articles
1.
Lin C, Marletaz F, Perez-Posada A, Martinez-Garcia P, Schloissnig S, Peluso P, et al.
PLoS Biol
. 2024 Jun;
22(6):e3002661.
PMID: 38829909
Deuterostomes are a monophyletic group of animals that includes Hemichordata, Echinodermata (together called Ambulacraria), and Chordata. The diversity of deuterostome body plans has made it challenging to reconstruct their ancestral...
2.
Nurk S, Koren S, Rhie A, Rautiainen M, Bzikadze A, Mikheenko A, et al.
Science
. 2022 Mar;
376(6588):44-53.
PMID: 35357919
Since its initial release in 2000, the human reference genome has covered only the euchromatic fraction of the genome, leaving important heterochromatic regions unfinished. Addressing the remaining 8% of the...
3.
Kronenberg Z, Rhie A, Koren S, Concepcion G, Peluso P, Munson K, et al.
Nat Commun
. 2021 Apr;
12(1):1935.
PMID: 33911078
Haplotype-resolved genome assemblies are important for understanding how combinations of variants impact phenotypes. To date, these assemblies have been best created with complex protocols, such as cultured cells that contain...
4.
Padgitt-Cobb L, Kingan S, Wells J, Elser J, Kronmiller B, Moore D, et al.
Plant Genome
. 2021 Feb;
14(1):e20072.
PMID: 33605092
Hop (Humulus lupulus L. var Lupulus) is a diploid, dioecious plant with a history of cultivation spanning more than one thousand years. Hop cones are valued for their use in...
5.
Garg S, Fungtammasan A, Carroll A, Chou M, Schmitt A, Zhou X, et al.
Nat Biotechnol
. 2020 Dec;
39(3):309-312.
PMID: 33288905
Haplotype-resolved or phased genome assembly provides a complete picture of genomes and their complex genetic variations. However, current algorithms for phased assembly either do not generate chromosome-scale phasing or require...
6.
Hon T, Mars K, Young G, Tsai Y, Karalius J, Landolin J, et al.
Sci Data
. 2020 Nov;
7(1):399.
PMID: 33203859
The PacBio HiFi sequencing method yields highly accurate long-read sequencing datasets with read lengths averaging 10-25 kb and accuracies greater than 99.5%. These accurate long reads can be used to...
7.
Soifer L, Fong N, Yi N, Ireland A, Lam I, Sooknah M, et al.
G3 (Bethesda)
. 2020 Jul;
10(9):2911-2925.
PMID: 32631951
In recent years, improved sequencing technology and computational tools have made genome assembly more accessible. Many approaches, however, generate either an unphased or only partially resolved representation of a diploid...
8.
Vollger M, Logsdon G, Audano P, Sulovari A, Porubsky D, Peluso P, et al.
Ann Hum Genet
. 2019 Nov;
84(2):125-140.
PMID: 31711268
The sequence and assembly of human genomes using long-read sequencing technologies has revolutionized our understanding of structural variation and genome organization. We compared the accuracy, continuity, and gene annotation of...
9.
Wenger A, Peluso P, Rowell W, Chang P, Hall R, Concepcion G, et al.
Nat Biotechnol
. 2019 Aug;
37(10):1155-1162.
PMID: 31406327
The DNA sequencing technologies in use today produce either highly accurate short reads or less-accurate long reads. We report the optimization of circular consensus sequencing (CCS) to improve the accuracy...
10.
Matthews B, Dudchenko O, Kingan S, Koren S, Antoshechkin I, Crawford J, et al.
Nature
. 2018 Nov;
563(7732):501-507.
PMID: 30429615
Female Aedes aegypti mosquitoes infect more than 400 million people each year with dangerous viral pathogens including dengue, yellow fever, Zika and chikungunya. Progress in understanding the biology of mosquitoes...