Paul P Jung
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Explore the profile of Paul P Jung including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
205
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Recent Articles
1.
Heins-Marroquin U, Jung P, Cordero-Maldonado M, Crawford A, Linster C
Brain Commun
. 2020 Sep;
1(1):fcz019.
PMID: 32954262
Mutations in () are causally linked to the rare neurodegenerative disorders Kufor-Rakeb syndrome, hereditary spastic paraplegia and neuronal ceroid lipofuscinosis. This suggests that ATP13A2, a lysosomal cation-transporting ATPase, plays a...
2.
Zhang Z, Jung P, Groues V, May P, Linster C, Glaab E
Gigascience
. 2019 May;
8(6).
PMID: 31141611
Background: Quantitative trait locus (QTL) mapping using bulk segregants is an effective approach for identifying genetic variants associated with phenotypes of interest in model organisms. By exploiting next-generation sequencing technology,...
3.
Becker-Kettern J, Paczia N, Conrotte J, Zhu C, Fiehn O, Jung P, et al.
FEBS J
. 2018 Aug;
285(18):3376-3401.
PMID: 30098110
NADHX and NADPHX are hydrated and redox inactive forms of the NADH and NADPH cofactors, known to inhibit several dehydrogenases in vitro. A metabolite repair system that is conserved in...
4.
Jung P, Zhang Z, Paczia N, Jaeger C, Ignac T, May P, et al.
NPJ Aging Mech Dis
. 2018 Mar;
4:3.
PMID: 29560271
Aging is a complex trait of broad scientific interest, especially because of its intrinsic link with common human diseases. Pioneering work on aging-related mechanisms has been made in , mainly...
5.
Jung P, Sigwalt A, Ohnuki S, de Montigny J, Ohya Y, Schacherer J
G3 (Bethesda)
. 2016 Feb;
6(4):1063-71.
PMID: 26888866
It is now clear that the exploration of the genetic and phenotypic diversity of nonmodel species greatly improves our knowledge in biology. In this context, we recently launched a population...
6.
Becker-Kettern J, Paczia N, Conrotte J, Kay D, Guignard C, Jung P, et al.
J Biol Chem
. 2016 Jan;
291(12):6036-58.
PMID: 26774271
The D or L form of 2-hydroxyglutarate (2HG) accumulates in certain rare neurometabolic disorders, and high D-2-hydroxyglutarate (D-2HG) levels are also found in several types of cancer. Although 2HG has...
7.
Jung P, Christian N, Kay D, Skupin A, Linster C
PLoS One
. 2015 Mar;
10(3):e0119807.
PMID: 25822370
In microorganisms, and more particularly in yeasts, a standard phenotyping approach consists in the analysis of fitness by growth rate determination in different conditions. One growth assay that combines high...
8.
Friedrich A, Jung P, Hou J, Neuveglise C, Schacherer J
PLoS One
. 2012 Nov;
7(10):e47834.
PMID: 23112855
Yeasts are leading model organisms for mitochondrial genome studies. The explosion of complete sequence of yeast mitochondrial (mt) genomes revealed a wide diversity of organization and structure between species. Recently,...
9.
Jung P, Friedrich A, Reisser C, Hou J, Schacherer J
G3 (Bethesda)
. 2012 Sep;
2(9):1103-11.
PMID: 22973548
Mitochondria are organelles, which play a key role in some essential functions, including respiration, metabolite biosynthesis, ion homeostasis, and apoptosis. The vast numbers of mitochondrial DNA (mtDNA) sequences of various...
10.
Ploidy influences cellular responses to gross chromosomal rearrangements in Saccharomyces cerevisiae
Jung P, Fritsch E, Blugeon C, Souciet J, Potier S, Lemoine S, et al.
BMC Genomics
. 2011 Jun;
12:331.
PMID: 21711526
Background: Gross chromosomal rearrangements (GCRs) such as aneuploidy are key factors in genome evolution as well as being common features of human cancer. Their role in tumour initiation and progression...