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Paul Mouncey

Explore the profile of Paul Mouncey including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 27
Citations 1057
Followers 0
Related Specialties
Critical Care
General Medicine
Pediatrics
Top 10 Co-Authors
Kathryn Rowan
David Harrison
Kathy Rowan
David A Harrison
Kerry Woolfall
Kathryn M Rowan
Paloma Ferrando-Vivas
Emma Gendall
Anton Kruger
Francois Lamontagne
Published In
J Intensive Care Soc
Acta Anaesthesiol Scand
Crit Care Med
Arch Dis Child
Br J Haematol
Affiliations
Soon will be listed here.
Recent Articles
1.
Heterogeneity in the Effect of Early Goal-Directed Therapy for Septic Shock: A Secondary Analysis of Two Multicenter International Trials
Shah F, Talisa V, Chang C, Triantafyllou S, Tang L, Mayr F, et al.
Crit Care Med . 2024 Oct; 53(1):e4-e14. PMID: 39440873
Objectives: The optimal approach for resuscitation in septic shock remains unclear despite multiple randomized controlled trials (RCTs). Our objective was to investigate whether previously uncharacterized variation across individuals in their...
2.
Guidance to inform research recruitment processes for studies involving critically ill patients
Woolfall K, Paddock K, Watkins M, Kearney A, Neville K, Frith L, et al.
J Intensive Care Soc . 2024 Sep; 25(1):95-101. PMID: 39323597
Clinical research in intensive care units (ICUs) is essential for improving treatments for critically ill patients. However, invitations to participate in clinical research in this situation pose numerous challenges. Studies...
3.
Oxidative stress, redox status and surfactant metabolism in mechanically ventilated patients receiving different approaches to oxygen therapy (MecROX): An observational study protocol for mechanistic evaluation
Dushianthan A, Martin D, Mouncey P, Shahid T, Lampro L, Johnson A, et al.
NIHR Open Res . 2024 Aug; 4:23. PMID: 39145107
Background: MecROX is a mechanistic sub-study of the UK-ROX trial which was designed to evaluate the clinical and cost-effectiveness of a conservative approach to oxygen therapy for invasively ventilated adults...
4.
Protocol for a Randomized Controlled Trial to Evaluate a Permissive Blood Pressure Target Versus Usual Care in Critically Ill Children with Hypotension (PRESSURE)
Darnell R, Brown A, Laing E, Edwards J, Harrison D, Manning J, et al.
Pediatr Crit Care Med . 2024 Apr; 25(7):629-637. PMID: 38629915
Objectives: Management of hypotension is a fundamental part of pediatric critical care, with cardiovascular support in the form of fluids or vasoactive drugs offered to every hypotensive child. However, optimal...
5.
Short-duration selective decontamination of the digestive tract infection control does not contribute to increased antimicrobial resistance burden in a pilot cluster randomised trial (the ARCTIC Study)
Kean I, Clark J, Zhang Z, Daubney E, White D, Ferrando-Vivas P, et al.
Gut . 2024 Jan; 73(6):910-921. PMID: 38253478
Objective: Selective decontamination of the digestive tract (SDD) is a well-studied but hotly contested medical intervention of enhanced infection control. Here, we aim to characterise the changes to the microbiome...
6.
Selective digestive tract decontamination to prevent healthcare associated infections in critically ill children: the PICNIC multicentre randomised pilot clinical trial
Pathan N, Woolfall K, Popa M, de la Fuente G, Ferrando-Vivas P, Brown A, et al.
Sci Rep . 2023 Dec; 13(1):21668. PMID: 38066012
Healthcare-associated infections (HCAIs) are a major cause of morbidity and mortality in critically ill children. Data from adult studies suggest Selective Decontamination of the Digestive tract (SDD) may reduce the...
7.
Critical illness related cardiac arrest: Protocol for an investigation of the incidence and outcome of cardiac arrest within intensive care units in the United Kingdom
Darnell R, Newell C, Edwards J, Gendall E, Harrison D, Sprinckmoller S, et al.
J Intensive Care Soc . 2023 Jun; 24(2):222-223. PMID: 37260435
No abstract available.
8.
Critical illness-related cardiac arrest: Protocol for an investigation of the incidence and outcome of cardiac arrest within intensive care units in the United Kingdom
Darnell R, Newell C, Edwards J, Gendall E, Harrison D, Sprinckmoller S, et al.
J Intensive Care Soc . 2023 Feb; 23(4):493-497. PMID: 36751345
Critical illness-related cardiac arrest (CIRCA) as a distinct entity is not well described epidemiologically. There is currently a knowledge gap regarding how many occur in the UK or the impact...
9.
High-Flow Nasal Cannula Therapy vs Continuous Positive Airway Pressure After Extubation and Liberation From Respiratory Support in Critically Ill Children-Reply
Ramnarayan P, Thomas K, Mouncey P
JAMA . 2022 Aug; 328(8):777. PMID: 35997738
No abstract available.
10.
A Machine-Learning Approach for Estimating Subgroup- and Individual-Level Treatment Effects: An Illustration Using the 65 Trial
Sadique Z, Grieve R, Diaz-Ordaz K, Mouncey P, Lamontagne F, ONeill S
Med Decis Making . 2022 May; 42(7):923-936. PMID: 35607982
This article examines a causal machine-learning approach, causal forests (CF), for exploring the heterogeneity of treatment effects, without prespecifying a specific functional form.The CF approach is considered in the reanalysis...